A Review of Rhazya stricta Decne Phytochemistry, Bioactivities, Pharmacological Activities, Toxicity, and Folkloric Medicinal Uses

被引:22
作者
Albeshri, Abdulaziz [1 ]
Baeshen, Nabih A. [1 ]
Bouback, Thamer A. [1 ,2 ]
Aljaddawi, Abdullah A. [1 ]
机构
[1] King Abdulaziz Univ, Fac Sci, Dept Biol Sci, Jeddah 21589, Saudi Arabia
[2] King Abdulaziz Univ, Princess Dr Najla Bint Saud Al Saud Ctr Excellenc, Jeddah 21589, Saudi Arabia
来源
PLANTS-BASEL | 2021年 / 10卷 / 11期
关键词
Rhazya stricta; folkloric medicine; alkaloid; phytochemicals; pharmacological activity; toxicity; PLANT; ALKALOIDS; EXTRACTS; NANOPARTICLES; GLUCOSE; LEAVES; RATS;
D O I
10.3390/plants10112508
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
The local medicinal plant Rhazya stricta Decne is reviewed for its folkloric medicinal, phytochemical, pharmacological, biological, and toxicological features. R. stricta has been used widely in different cultures for various medical disorders. The phytochemical studies performed on the R. stricta extract revealed many alkaloidal and fatty acid compounds. Moreover, several flavonoid and terpenoid compounds were also detected. Pharmacological activates of R. stricta extracts are approved to possess antimicrobial, antioxidant, anticancer, antidiabetic, and antihypertensive activities. Additionally, R. stricta extract was found to hold biological activates such as larvicidal and phytoremediation activates R. stricta extract was found to be toxic, genotoxic, and mutagenic. R. stricta contains novel phytochemical compounds that have not been investigated pharmacologically. Further research is needed through in vitro and in vivo experiments to pave the road for these compounds for medical, veterinary, and ecological uses.
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页数:18
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