School Milk and Risk of Colorectal Cancer: A National Case-Control Study

被引:18
作者
Cox, Brian [1 ]
Sneyd, Mary J. [1 ]
机构
[1] Univ Otago, Dunedin Sch Med, Hugh Adam Canc Epidemiol Unit, Dept Prevent & Social Med, Dunedin 9054, New Zealand
关键词
calcium; case-control studies; child; colorectal neoplasms; milk; NORMAL COLON MUCOSA; CALCIUM SUPPLEMENTATION; VITAMIN-D; PREVENTION; ADENOMA;
D O I
10.1093/aje/kwq390
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
To determine whether school milk consumption in childhood decreased the risk of adult colorectal cancer, the authors conducted a national population-based, case-control study of 562 cases and 571 controls. The authors identified new cases of colorectal cancer in 2007 among people aged 30-69 years from the New Zealand Cancer Registry. Controls were randomly selected from the electoral rolls and frequency matched to cases in 5-year age groups. Participation in school milk programs was associated with a reduced odds ratio for colorectal cancer (odds ratio (OR) = 0.70, 95% confidence interval (CI): 0.51, 0.96). Odds ratios decreased with increasing numbers of bottles of milk drunk compared with no school milk (for 1-799 bottles, OR = 1.04, 95% CI: 0.66, 1.67; for 800-1,199 bottles, OR = 0.81, 95% CI: 0.51, 1.29; for 1,200-1,599 bottles, OR = 0.62, 95% CI: 0.41, 0.93; for 1,600-1,799 bottles, OR = 0.57, 95% CI: 0.37, 0.90; and for 1,800 or more bottles, OR = 0.62, 95% CI: 0.41, 0.96). Participation in school milk programs in New Zealand was associated with a 2.1% reduction (95% CI: 0.7, 3.5) in the odds ratio for colorectal cancer for every 100 half-pint bottles drunk (1 half-pint bottle = 284 mL).
引用
收藏
页码:394 / 403
页数:10
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