Persistent SARS-CoV-2 Alpha Variant Infection in Immunosuppressed Patient, France, February 2022

被引:4
作者
Fourati, Slim [1 ]
Gautier, Guillaume [2 ]
Chovelon, Myriam [2 ]
Soulier, Alexandre [1 ]
N'Debi, Melissa [1 ]
Demontant, Vanessa [1 ]
Kennel, Celine [2 ]
Rodriguez, Christophe [1 ]
Pawlotsky, Jean-Michel [1 ]
机构
[1] Univ Paris Est, Hop Henri Mondor APHP, Creteil, France
[2] William Morey Gen Hosp, Chalon Sur Saone, France
关键词
D O I
10.3201/eid2807.220467
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
We describe persistent circulation of SARS-CoV-2 Alpha variant in an immunosuppressed patient in France during February 2022. The virus had a new pattern of mutation accumulation. The ongoing circulation of previous variants of concern could lead to reemergence of variants with the potential to propagate future waves of infection.
引用
收藏
页码:1512 / 1515
页数:4
相关论文
共 9 条
[1]   Case Study: Prolonged Infectious SARS-CoV-2 Shedding from an Asymptomatic Immunocompromised Individual with Cancer [J].
Avanzato, Victoria A. ;
Matson, M. Jeremiah ;
Seifert, Stephanie N. ;
Pryce, Rhys ;
Williamson, Brandi N. ;
Anzick, Sarah L. ;
Barbian, Kent ;
Judson, Seth D. ;
Fischer, Elizabeth R. ;
Martens, Craig ;
Bowden, Thomas A. ;
de Wit, Emmie ;
Riedo, Francis X. ;
Munster, Vincent J. .
CELL, 2020, 183 (07) :1901-+
[2]   SARS-CoV-2 prolonged infection during advanced HIV disease evolves extensive immune escape [J].
Cele, Sandile ;
Karim, Farina ;
Lustig, Gila ;
San, James Emmanuel ;
Hermanus, Tandile ;
Tegally, Houriiyah ;
Snyman, Jumari ;
Moyo-Gwete, Thandeka ;
Wilkinson, Eduan ;
Bernstein, Mallory ;
Khan, Khadija ;
Hwa, Shi-Hsia ;
Tilles, Sasha W. ;
Singh, Lavanya ;
Giandhari, Jennifer ;
Mthabela, Ntombifuthi ;
Mazibuko, Matilda ;
Ganga, Yashica ;
Gosnell, Bernadett, I ;
Karim, Salim S. Abdool ;
Hanekom, Willem ;
Van Voorhis, Wesley C. ;
Ndung'u, Thumbi ;
Lessells, Richard J. ;
Moore, Penny L. ;
Moosa, Mahomed-Yunus S. ;
de Oliveira, Tulio ;
Sigal, Alex .
CELL HOST & MICROBE, 2022, 30 (02) :154-+
[3]   Persistence and Evolution of SARS-CoV-2 in an Immunocompromised Host [J].
Choi, Bina ;
Choudhary, Manish C. ;
Regan, James ;
Sparks, Jeffrey A. ;
Padera, Robert F. ;
Qiu, Xueting ;
Solomon, Isaac H. ;
Kuo, Hsiao-Hsuan ;
Boucau, Julie ;
Bowman, Kathryn ;
Das Adhikari, U. ;
Winkler, Marisa L. ;
Mueller, Alisa A. ;
Hsu, Tiffany Y. -T. ;
Desjardins, Michael ;
Baden, Lindsey R. ;
Chan, Brian T. ;
Walker, Bruce D. ;
Lichterfeld, Mathias ;
Brigl, Manfred ;
Kwon, Douglas S. ;
Kanjilal, Sanjat ;
Richardson, Eugene T. ;
Jonsson, A. Helena ;
Alter, Galit ;
Barczak, Amy K. ;
Hanage, William P. ;
Yu, Xu G. ;
Gaiha, Gaurav D. ;
Seaman, Michael S. ;
Cernadas, Manuela ;
Li, Jonathan Z. .
NEW ENGLAND JOURNAL OF MEDICINE, 2020, 383 (23) :2291-2293
[4]   SARS-CoV-2 Variants in Patients with Immunosuppression [J].
Corey, Lawrence ;
Beyrer, Chris ;
Cohen, Myron S. ;
Michael, Nelson L. ;
Bedford, Trevor ;
Rolland, Morgane .
NEW ENGLAND JOURNAL OF MEDICINE, 2021, 385 (06) :562-566
[5]   SARS-CoV-2 variants with reduced infectivity and varied sensitivity to the BNT162b2 vaccine are developed during the course of infection [J].
Khateeb, Dina ;
Gabrieli, Tslil ;
Sofer, Bar ;
Hattar, Adi ;
Cordela, Sapir ;
Chaouat, Abigael ;
Spivak, Ilia ;
Lejbkowicz, Izabella ;
Almog, Ronit ;
Mandelboim, Michal ;
Bar-On, Yotam .
PLOS PATHOGENS, 2022, 18 (01)
[6]   Different Within-Host Viral Evolution Dynamics in Severely Immunosuppressed Cases with Persistent SARS-CoV-2 [J].
Perez-Lago, Laura ;
Aldamiz-Echevarria, Teresa ;
Garcia-Martinez, Rita ;
Perez-Latorre, Leire ;
Herranz, Marta ;
Sola-Campoy, Pedro ;
Suarez-Gonzalez, Julia ;
Martinez-Laperche, Carolina ;
Comas, Inaki ;
Gonzalez-Candelas, Fernando ;
Catalan, Pilar ;
Munoz, Patricia ;
Garcia de Viedma, Dario .
BIOMEDICINES, 2021, 9 (07)
[7]   SARS-CoV-2 Variants in Immunocompromised Patient Given Antibody Monotherapy [J].
Truffot, Aurelie ;
Andreani, Julien ;
Le Marechal, Marion ;
Caporossi, Alban ;
Epaulard, Olivier ;
Germi, Raphaele ;
Poignard, Pascal ;
Larrat, Sylvie .
EMERGING INFECTIOUS DISEASES, 2021, 27 (10) :2725-2728
[8]   Intra-host variation and evolutionary dynamics of SARS-CoV-2 populations in COVID-19 patients [J].
Wang, Yanqun ;
Wang, Daxi ;
Zhang, Lu ;
Sun, Wanying ;
Zhang, Zhaoyong ;
Chen, Weijun ;
Zhu, Airu ;
Huang, Yongbo ;
Xiao, Fei ;
Yao, Jinxiu ;
Gan, Mian ;
Li, Fang ;
Luo, Ling ;
Huang, Xiaofang ;
Zhang, Yanjun ;
Sook-san Wong ;
Cheng, Xinyi ;
Ji, Jingkai ;
Ou, Zhihua ;
Xiao, Minfeng ;
Li, Min ;
Li, Jiandong ;
Ren, Peidi ;
Deng, Ziqing ;
Zhong, Huanzi ;
Xu, Xun ;
Song, Tie ;
Mok, Chris Ka Pun ;
Peiris, Malik ;
Zhong, Nanshan ;
Zhao, Jingxian ;
Li, Yimin ;
Li, Junhua ;
Zhao, Jincun .
GENOME MEDICINE, 2021, 13 (01)
[9]   Within-host evolution of SARS-CoV-2 in an immunosuppressed COVID-19 patient as a source of immune escape variants [J].
Weigang, Sebastian ;
Fuchs, Jonas ;
Zimmer, Gert ;
Schnepf, Daniel ;
Kern, Lisa ;
Beer, Julius ;
Luxenburger, Hendrik ;
Ankerhold, Jakob ;
Falcone, Valeria ;
Kemming, Janine ;
Hofmann, Maike ;
Thimme, Robert ;
Neumann-Haefelin, Christoph ;
Ulferts, Svenja ;
Grosse, Robert ;
Hornuss, Daniel ;
Tanriver, Yakup ;
Rieg, Siegbert ;
Wagner, Dirk ;
Huzly, Daniela ;
Schwemmle, Martin ;
Panning, Marcus ;
Kochs, Georg .
NATURE COMMUNICATIONS, 2021, 12 (01)