"Haemochromatotic" characteristics of the human BEL-7402 cell line

被引:3
作者
Xu, Anjian [1 ,2 ,3 ]
Li, Yanmeng [1 ]
Chen, Wei [1 ]
Li, Xiaojin [1 ,2 ]
Zhang, Wei [2 ,4 ,5 ]
Li, Siwen [1 ]
Wu, Lina [4 ,5 ]
Wu, Zhen [4 ,5 ]
Zhang, Bei [1 ]
Ou, Xiaojuan [2 ,3 ,4 ,5 ]
Huang, Jian [1 ,2 ,3 ,4 ,5 ]
机构
[1] Capital Med Univ, Beijing Friendship Hosp, Expt Ctr, Beijing, Peoples R China
[2] Capital Med Univ, Clin Res Ctr Rare Liver Dis, Beijing, Peoples R China
[3] Capital Med Univ, Natl Clin Res Ctr Digest Dis, Beijing, Peoples R China
[4] Capital Med Univ, Beijing Friendship Hosp, Liver Res Ctr, Beijing, Peoples R China
[5] Beijing Key Lab Translat Med Liver Cirrhosis, Beijing, Peoples R China
基金
中国国家自然科学基金;
关键词
hereditary haemochromatosis; HFE2; BEL-7402 cell line; HAMP; mutant; HEREDITARY HEMOCHROMATOSIS; PLASMA-MEMBRANE; HEMOJUVELIN; HEPCIDIN; MANAGEMENT; MUTATIONS; GENES;
D O I
10.1111/bjh.14952
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页码:302 / 306
页数:5
相关论文
共 10 条
[1]   Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression [J].
Babitt, JL ;
Huang, FW ;
Wrighting, DM ;
Xia, Y ;
Sidis, Y ;
Samad, TA ;
Campagna, JA ;
Chung, RT ;
Schneyer, AL ;
Woolf, CJ ;
Andrews, NC ;
Lin, HY .
NATURE GENETICS, 2006, 38 (05) :531-539
[2]   Diagnosis and Management of Hemochromatosis: 2011 Practice Guideline by the American Association for the Study of Liver Diseases [J].
Bacon, Bruce R. ;
Adams, Paul C. ;
Kowdley, Kris V. ;
Powell, Lawrie W. ;
Tavill, Anthony S. .
HEPATOLOGY, 2011, 54 (01) :328-343
[3]  
CHEN R, 1980, SCI SINICA, V23, P236
[4]   Hemojuvelin and Hepcidin Genes Sequencing in Brazilian Patients with Primary Iron Overload [J].
Junior de Lima Santos, Paulo Caleb ;
Pereira, Alexandre C. ;
Cancado, Rodolfo D. ;
Schettert, Isolmar T. ;
Hirata, Rosario D. C. ;
Hirata, Mario H. ;
Figueiredo, Maria Stella ;
Chiattone, Carlos S. ;
Krieger, Jose E. ;
Guerra-Shinohara, Elvira M. .
GENETIC TESTING AND MOLECULAR BIOMARKERS, 2010, 14 (06) :803-806
[5]   Non-classical hereditary hemochromatosis in Portugal: novel mutations identified in iron metabolism-related genes [J].
Mendes, Ana Isabel ;
Ferro, Ana ;
Martins, Rute ;
Picanco, Isabel ;
Gomes, Susana ;
Cerqueira, Rute ;
Correia, Manuel ;
Nunes, Antonio Robalo ;
Esteves, Jorge ;
Fleming, Rita ;
Faustino, Paula .
ANNALS OF HEMATOLOGY, 2009, 88 (03) :229-234
[6]   Hemojuvelin N-terminal mutants reach the plasma membrane but do not activate the hepcidin response [J].
Pagani, Alessia ;
Silvestri, Laura ;
Nai, Antonella ;
Camaschella, Clara .
HAEMATOLOGICA-THE HEMATOLOGY JOURNAL, 2008, 93 (10) :1466-1472
[7]   Genetics, Genetic Testing, and Management of Hemochromatosis: 15 Years Since Hepcidin [J].
Pietrangelo, Antonello .
GASTROENTEROLOGY, 2015, 149 (05) :1240-+
[8]   Hereditary hemochromatosis: Mutations in genes involved in iron homeostasis in Brazilian patients [J].
Santos, Paulo C. J. L. ;
Cancado, Rodolfo D. ;
Pereira, Alexandre C. ;
Schettert, Isolmar T. ;
Soares, Renata A. G. ;
Pagliusi, Regina A. ;
Hirata, Rosario D. C. ;
Hirata, Mario H. ;
Teixeira, Ana C. ;
Figueiredo, Maria Stella ;
Chiattone, Carlos S. ;
Krieger, Jose E. ;
Guerra-Shinohara, Elvira M. .
BLOOD CELLS MOLECULES AND DISEASES, 2011, 46 (04) :302-307
[9]   Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis [J].
Silvestri, Laura ;
Pagani, Alessia ;
Fazi, Claudia ;
Gerardi, Gianmario ;
Levi, Sonia ;
Arosio, Paolo ;
Camaschella, Clara .
BLOOD, 2007, 109 (10) :4503-4510
[10]   Huh-7: A Human "Hemochromatotic" Cell Line [J].
Vecchi, Chiara ;
Montosi, Giuliana ;
Pietrangelo, Antonello .
HEPATOLOGY, 2010, 51 (02) :654-659