Self-Assembling Protein Nanoparticles: implications for HIV-1 vaccine development

被引:12
作者
Karch, Christopher P. [1 ,2 ]
Matyas, Gary R. [1 ]
Burkhard, Peter [3 ]
Beck, Zoltan [1 ,2 ]
机构
[1] Walter Reed Army Inst Res, US Mil HIV Res Program, Lab Adjuvant & Antigen Res, 503 Robert Grant Ave, Silver Spring, MD 20910 USA
[2] Henry M Jackson Fdn Adv Mil Med, 6720A Rockledge Dr, Bethesda, MD 20817 USA
[3] Alpha O Peptides, Lorracherstr 50, CH-4125 Riehen, Switzerland
关键词
antigen density; conformational antibody; HIV-1; nanoparticle; SAPN; trimeric epitope; vaccine; PROTECTION; EFFICACY; DESIGN;
D O I
10.2217/nnm-2018-0222
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
[No abstract available]
引用
收藏
页码:2121 / 2126
页数:6
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