Investigation of photothermolysis therapy of human skin diseases using optical phantoms

被引：0

作者：

Jedrzejewska-Szczerska, M. ^{[1
]}

Wrobel, M. S. ^{[1
]}

Galla, S. ^{[1
]}

Popov, A. P. ^{[2
]}

Bykov, A. V. ^{[2
]}

Tuchin, V. V. ^{[2
,3
,4
]}

Cenian, A. ^{[5
]}

机构：

[1] Gdansk Univ Technol, Fac Elect Telecommun & Informat, Dept Metrol & Optoelect, PL-80233 Gdansk, Poland

[2] Univ Oulu, Fac Informat Technol & Elect Engn, Optoelect & Measurement Tech Lab, FI-90014 Oulu, Finland

[3] Saratov NG Chernyshevskii State Univ, Res Educ Inst Opt & Biophoton, Saratov 410012, Russia

[4] Russian Acad Sci, Inst Precise Mech & Control, Saratov 410028, Russia

[5] Polish Acad Sci, Szewalski Inst Fluid Flow Machinery, Phys Aspects Ecoenergy Dept, PL-80952 Gdansk, Poland

来源：

18TH INTERNATIONAL SCHOOL ON QUANTUM ELECTRONICS: LASER PHYSICS AND APPLICATIONS | 2015年 / 9447卷

关键词：

optical skin phantom; Nd:YAG laser; photothermolysis; neurofibroma; hemangiomas; thermography; LASER;

D O I：

10.1117/12.2177790

中图分类号：

TM [电工技术]; TN [电子技术、通信技术];

学科分类号：

0808 ; 0809 ;

摘要：

Dermatological diseases, such as neurofibroma (Recklinghausen disease) or hemangiomas can be efficiently treated using photothermolysis from laser irradiation. We have utilized a developed 975 nm fiber diode laser as a low-cost alternative over common Nd:YAG lasers. This paper describes the investigations of interaction of 975 nm diode laser radiation-pulses with optical skin phantoms which were designed and manufactured in our laboratory. Such phantoms match the scattering and absorption coefficients of real human skin. Spatial and temporal temperature evolutions during laser irradiation with various laser settings (pulsed and CW mode), were recorded by an IR camera. Subsequent analysis yielded optimum choice of parameters for laser therapy of coetaneous lesions.

引用

页数：6

共 12 条

[1] OPTICAL PROPERTIES OF SKIN, SUBCUTANEOUS, AND MUSCLE TISSUES: A REVIEW [J].

Bashkatov, Alexey N. ;

Genina, Elina A. ;

Tuchin, Valery V. .

JOURNAL OF INNOVATIVE OPTICAL HEALTH SCIENCES, 2011, 4 (01) :9-38

[2] Determination of refractive index dispersion using fiber-optic low-coherence Fabry-Perot interferometer: implementation and validation [J].

Karpienko, Katarzyna ;

Wrobel, Maciej S. ;

Jedrzejewska-Szczerska, Malgorzata .

OPTICAL ENGINEERING, 2014, 53 (07)

[3] Modeling of non-contact temperature measurement system using multiwavelength pyrometry [J].

Mazikowski, A ;

Hypszer, R ;

Jedrzejewska-Szczerska, M .

OPTOELECTRONIC AND ELCTRONIC SENSORS IV, 2001, 4516 :120-+

[4] Pulsed dermatologic 20W diode-laser emitting at 975 nm [J].

Piechowski, L. ;

Cenian, W. ;

Sawczak, M. ;

Cenian, A. .

LASER TECHNOLOGY 2012: APPLICATIONS OF LASERS, 2013, 8703

[5] Review of tissue simulating phantoms for optical spectroscopy, imaging and dosimetry [J].

Pogue, Brian W. ;

Patterson, Michael S. .

JOURNAL OF BIOMEDICAL OPTICS, 2006, 11 (04)

[6] DETERMINING THE OPTICAL-PROPERTIES OF TURBID MEDIA BY USING THE ADDING-DOUBLING METHOD [J].

PRAHL, SA ;

VANGEMERT, MJC ;

WELCH, AJ .

APPLIED OPTICS, 1993, 32 (04) :559-568

[7] Multi-layer silicone phantoms for the evaluation of quantitative optical techniques in skin imaging [J].

Saager, Rolf B. ;

Kondru, Clement ;

Au, Kendrew ;

Sry, Kelly ;

Ayers, Frederick ;

Durkin, Anthony J. .

DESIGN AND PERFORMANCE VALIDATION OF PHANTOMS USED IN CONJUNCTION WITH OPTICAL MEASUREMENT OF TISSUE II, 2010, 7567

[8] Mathematical modeling of selective photothermolysis to aid the treatment of vascular malformations and hemangioma with pulsed dye laser [J].

Shafirstein, Gal ;

Buckmiller, Lisa M. ;

Waner, Milton ;

Baeumler, Wolfgang .

LASERS IN MEDICAL SCIENCE, 2007, 22 (02) :111-118

[9]

Szymanczyk J., 1998, MEDIPRESS DERMATOLOG, V3, P12

[10]

Tuchin VV., 1997, PHYS-USP+, V40, P495, DOI [DOI 10.3367/UFNR.0167.199705C.0517, 10.1070/PU1997v040n05ABEH000236, DOI 10.1070/PU1997V040N05ABEH000236]

← 1 2 →