Effects. of a fennented milk drink containing Lactobacillus casei strain Shirota on the immune system in healthy human subjects

被引：133

作者：

Nagao, F

Nakayama, M

Muto, T

Okumura, K

机构：

[1] Juntendo Univ, Sch Med, Dept Immunol, Bunkyo Ku, Tokyo 1138421, Japan

[2] Juntendo Univ, Sch Med, Dept Publ Hlth, Bunkyo Ku, Tokyo 1138421, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2000年 / 64卷 / 12期

关键词：

fermented milk; immune system; NK cell activity; Lactobacillus casei strain Shirota;

D O I：

10.1271/bbb.64.2706

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nine healthy volunteers drank fermented milk containing 4x10(10) live cells of Lactobacillus casei strain Shirota daily for 3 weeks, and their NK activity and other immunological functions were measured, NK activity significantly increased (p<0.01) 3 weeks after the start of intake and remained elevated for the next 3 weeks. The effect was particularly prominent in low-NK-individuals.

引用

收藏

页码：2706 / 2708

页数：3

相关论文

共 23 条

[1] PROPHYLACTIC EFFECT OF A LACTOBACILLUS-CASEI PREPARATION ON THE RECURRENCE OF SUPERFICIAL BLADDER-CANCER [J].

ASO, Y ;

AKAZAN, H .

UROLOGIA INTERNATIONALIS, 1992, 49 (03) :125-129

[2] PREVENTIVE EFFECT OF A LACTOBACILLUS-CASEI PREPARATION ON THE RECURRENCE OF SUPERFICIAL BLADDER-CANCER IN A DOUBLE-BLIND TRIAL [J].

ASO, Y ;

AKAZA, H ;

KOTAKE, T ;

TSUKAMOTO, T ;

IMAI, K ;

NAITO, S .

EUROPEAN UROLOGY, 1995, 27 (02) :104-109

[3] THE EFFECT OF MICROBIAL-FLORA, DIET, AND AGE ON THE TUMORICIDAL ACTIVITY OF NATURAL-KILLER CELLS [J].

BARTIZAL, KF ;

SALKOWSKI, C ;

PLEASANTS, JR ;

BALISH, E .

JOURNAL OF LEUKOCYTE BIOLOGY, 1984, 36 (06) :739-750

[4]

BARTIZAL KF, 1983, J RETICULOENDOTH SOC, V33, P381

[5] EUROPIUM-LABELED TARGET-CELLS IN AN ASSAY OF NATURAL-KILLER CELL-ACTIVITY .1. A NOVEL NONRADIOACTIVE METHOD BASED ON TIME-RESOLVED FLUORESCENCE [J].

BLOMBERG, K ;

GRANBERG, C ;

HEMMILA, I ;

LOVGREN, T .

JOURNAL OF IMMUNOLOGICAL METHODS, 1986, 86 (02) :225-229

[6]

Cebra J J, 1998, Dev Immunol, V6, P13, DOI 10.1155/1998/68382

[7] Stimulation of the immune system by lactic cultures [J].

Gill, HS .

INTERNATIONAL DAIRY JOURNAL, 1998, 8 (5-6) :535-544

[8] NATURAL-KILLER CELLS - THEIR ROLE IN DEFENSES AGAINST DISEASE [J].

HERBERMAN, RB ;

ORTALDO, JR .

SCIENCE, 1981, 214 (4516) :24-30

[9] EXERCISE AND THE IMMUNE-SYSTEM - A MODEL OF THE STRESS-RESPONSE [J].

HOFFMANGOETZ, L ;

PEDERSEN, BK .

IMMUNOLOGY TODAY, 1994, 15 (08) :382-387

[10] EFFECTS OF ORAL-ADMINISTRATION OF LACTOBACILLUS-CASEI ON ANTITUMOR RESPONSES INDUCED BY TUMOR RESECTION IN MICE [J].

KATO, I ;

ENDO, K ;

YOKOKURA, T .

INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY, 1994, 16 (01) :29-36