Effects of low dose tryptophan depletion on emotional processing in dieters

被引：5

作者：

Pringle, A. ^{[1
]}

Cooper, M. J. ^{[2
]}

Browning, M. ^{[1
]}

Harmer, C. J. ^{[1
]}

机构：

[1] Univ Oxford, Dept Psychiat, Oxford OX1 2JD, England

[2] Univ Oxford, Oxford Doctoral Course Clin Psychol, Oxford OX1 2JD, England

来源：

EATING BEHAVIORS | 2012年 / 13卷 / 02期

基金：

英国医学研究理事会;

关键词：

Serotonin; Emotional processing; Tryptophan depletion; Attention; Eating disorders; EATING-DISORDERS; ANOREXIA-NERVOSA; ATTENTIONAL BIASES; HEALTHY-VOLUNTEERS; BULIMIA-NERVOSA; DEPRESSION; SYMPTOMS; RELAPSE; THREAT; CUES;

D O I：

10.1016/j.eatbeh.2011.12.005

中图分类号：

B849 [应用心理学];

学科分类号：

040203 ;

摘要：

Biased processing of ED-relevant stimuli (eg Fairburn, Shafran, & Cooper, 1999) and 5-HT function (Kaye, Fudge, & Paulus, 2009) are implicated in vulnerability to and the maintenance of eating disorders (EDs), but it is not known if these findings are connected: Could manipulating 5-HT function affect the processing of ED-relevant stimuli? To address this question we assessed emotional processing in female dieters (T + n = 12, T - n = 14) following acute low dose tryptophan depletion. AID increased interference in the masked condition of the emotional Stroop to all negative emotional stimuli, in the absence of any other differences in emotional processing. These results suggest that ATD affects the processing of some negative (including ED-relevant) stimuli, and that reduced 5-HT function may be involved in some aspects of psychological vulnerability to EDs. (C) 2012 Elsevier Ltd. All rights reserved.

引用

页码：154 / 157

页数：4

共 50 条

[21] Effects of acute tryptophan depletion on mood in bulimia nervosa
Kaye, WH
Gendall, KA
Fernstrom, MH
Fernstrom, JD
McConaha, CW
Weltzin, TE
BIOLOGICAL PSYCHIATRY, 2000, 47 (02) : 151 - 157
[22] The effect of acute tryptophan depletion on emotional distraction and subsequent memory
Wang, Lihong
Mullette-Gillman, O'Dhaniel A.
Gadde, Kishore M.
Kuhn, Cynthia M.
McCarthy, Gregory
Huettel, Scott A.
SOCIAL COGNITIVE AND AFFECTIVE NEUROSCIENCE, 2009, 4 (04) : 357 - 368
[23] Effect of low-dose acute tryptophan depletion on the specificity of autobiographical memory in healthy subjects with a family history of depression
Hamid A. Alhaj
Matthew Selman
Victoria Jervis
Jacqui Rodgers
Stephen Barton
R. Hamish McAllister-Williams
Psychopharmacology, 2012, 222 : 285 - 292
[24] EFFECTS OF TRYPTOPHAN DEPLETION IN PANIC DISORDER
GODDARD, AW
SHOLOMSKAS, DE
WALTON, KE
AUGERI, FM
CHARNEY, DS
HENINGER, GR
GOODMAN, WK
PRICE, LH
BIOLOGICAL PSYCHIATRY, 1994, 36 (11) : 775 - 777
[25] No clear effects of acute tryptophan depletion on processing affective prosody in male adults with ADHD
Grabemann, M.
Mette, C.
Zimmermann, M.
Heinrich, V.
Uekermann, J.
Wiltfang, J.
Abdel-Hamid, M.
Zepf, F. D.
Kis, B.
ACTA PSYCHIATRICA SCANDINAVICA, 2013, 128 (02) : 142 - 148
[26] Effects of tryptophan depletion on anxiety induced by simulated public speaking
Monteiro-dos-Santos, PC
Graeff, FG
dos-Santos, JE
Ribeiro, RPP
Guimaraes, FS
Zuardi, AW
BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH, 2000, 33 (05) : 581 - 587
[27] The effects of tryptophan depletion on mood and psychiatric symptoms
Van der Does, AJW
JOURNAL OF AFFECTIVE DISORDERS, 2001, 64 (2-3) : 107 - 119
[28] Low-dose tryptophan depletion in recovered depressed women induces impairments in autobiographical memory specificity
Haddad, Anneke D. M.
Williams, J. Mark G.
McTavish, Sarah F. B.
Harmer, Catherine J.
PSYCHOPHARMACOLOGY, 2009, 207 (03) : 499 - 508
[29] Effects of acute tryptophan depletion on executive function in healthy male volunteers
Gallagher, Peter
Massey, Anna E.
Young, Allan H.
McAllister-Williams, R. Hamish
BMC PSYCHIATRY, 2003, 3 (1)
[30] The effects of acute tryptophan depletion on neuropsychological function
Hughes, JH
Gallagher, P
Stewart, ME
Matthews, D
Kelly, TP
Young, AH
JOURNAL OF PSYCHOPHARMACOLOGY, 2003, 17 (03) : 300 - 309

← 1 2 3 4 5 →