Spinal Cord Stimulation for the Treatment of Chronic Pain Reduces Opioid Use and Results in Superior Clinical Outcomes When Used Without Opioids

被引:44
作者
Gee, Lucy [1 ]
Smith, Heather C. [2 ]
Ghulam-Jelani, Zohal [1 ,2 ]
Khan, Hirah [2 ]
Prusik, Julia [1 ,2 ]
Feustel, Paul J. [1 ]
McCallum, Sarah E. [1 ]
Pilitsis, Julie G. [1 ,2 ]
机构
[1] Albany Med Ctr, Dept Neurosci & Expt Therapeut, Albany, NY USA
[2] Albany Med Ctr, Dept Neurosurg, Albany, NY USA
基金
美国国家卫生研究院;
关键词
Neuromodulation; Narcotic use; Pain management; UNITED-STATES; BACK; PREVALENCE; MANAGEMENT;
D O I
10.1093/neuros/nyy065
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
BACKGROUND: Chronic pain causes a significant burden to the US health care system, is difficult to treat, and remains a significant contributor to increased opioid use in the United States. Spinal cord stimulation (SCS) has been FDA approved for the treatment of chronic pain. OBJECTIVE: To evaluate the hypothesis that SCS reduces opioid use, and alone maintains clinical outcome measures of pain and psychosocial determinants of health. METHODS: In this prospective cohort study, we evaluated 86 patients undergoing SCS surgery for the treatment of chronic pain between September 2012 andAugust 2015. Preoperatively and postoperatively, patients completed the Numerical Rating Scale (NRS), McGill Pain Questionnaire (MPQ), Pain Catastrophizing Scale (PCS), Oswestry Disability Index (ODI), and Beck's Depression Inventory (BDI). VAS scores were retrospectively analyzed. RESULTS: Fifty-three patients used opioids before SCS implantation. The 33 nonusers had lowermean VAS, NRS, and ODI scores than both opioid groups at 1 yr and improved significantly at 1 yr on the VAS (P<.001), NRS (P<.001), MPQ (P=.002), PCS (P<.001), BDI (P=.04), and ODI (P=.002). After surgery, 41.5% remained opioids and 58.5% reduced/eliminated use. Discontinued (n=29) or reduced (n=2) use resulted in VAS, NRS, total MPQ, and ODI score reduction (P<.001, P=.002, P=.002, and P=.009 respectively). At 1 yr, survey scores in opioid users were unchanged. There was no difference between groups in revision or failure rates. CONCLUSION: Sixty-four percent of patientswhowere using opioids prior to SCS reduced (n=2) or eliminated opioid use (n=29) at 1 yr postoperatively. Patients who eliminated opioid use or never used opioids had superior clinical outcomes to those who continued use.
引用
收藏
页码:217 / 225
页数:9
相关论文
共 35 条
[1]   Treatment Options for Failed Back Surgery Syndrome Patients With Refractory Chronic Pain: An Evidence Based Approach [J].
Amirdelfan, Kasra ;
Webster, Lynn ;
Poree, Lawrence ;
Sukul, Vishad ;
McRoberts, Porter .
SPINE, 2017, 42 (14) :S41-S52
[2]  
[Anonymous], ISTOP PMP INTERNET S
[3]   Recent advances in spinal cord stimulation for pain treatment [J].
Baranidharan, Ganesan ;
Titterington, John .
PAIN MANAGEMENT, 2016, 6 (06) :581-589
[4]   Psychological Factors as Outcome Predictors for Spinal Cord Stimulation [J].
Bendinger, Tomasz ;
Plunkett, Nick ;
Poole, Debbie ;
Turnbull, David .
NEUROMODULATION, 2015, 18 (06) :465-471
[5]   High-Frequency Spinal Cord Stimulation for Chronic Pain: Pre-Clinical Overview and Systematic Review of Controlled Trials [J].
Bicket, Mark C. ;
Dunn, Roger Y. ;
Ahmed, Shihab U. .
PAIN MEDICINE, 2016, 17 (12) :2326-2336
[6]   Management of chronic pain using complementary and integrative medicine [J].
Chen, Lucy ;
Michalsen, Andreas .
BMJ-BRITISH MEDICAL JOURNAL, 2017, 357 :j1284
[7]   SPINAL-CORD STIMULATION IN FAILED BACK SURGERY SYNDROME [J].
DELAPORTE, C ;
VANDEKELFT, E .
PAIN, 1993, 52 (01) :55-61
[8]   Spinal cord stimulation: A valuable treatment for chronic failed back surgery patients [J].
Devulder, J ;
DeLaat, M ;
VanBastelaere, M ;
Rolly, G .
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT, 1997, 13 (05) :296-301
[9]   A psychometric evaluation of the Beck Depression Inventory - II [J].
Dozois, DJA ;
Dobson, KS ;
Ahnberg, JL .
PSYCHOLOGICAL ASSESSMENT, 1998, 10 (02) :83-89
[10]   Managing Chronic Pain With Spinal Cord Stimulation [J].
Epstein, Lawrence J. ;
Palmieri, Marco .
MOUNT SINAI JOURNAL OF MEDICINE, 2012, 79 (01) :123-132