Colonoscopy effects on serum prostate specific antigen levels

被引:4
作者
Barbatzas, C. [2 ]
Dellis, A. [1 ]
Grivas, I. [2 ]
Trakas, N. [3 ]
Ekonomou, A. [3 ]
Kostakopoulos, A. [1 ]
机构
[1] Univ Athens, Dept Urol, Athens, Greece
[2] Univ Athens, Dept Gastroenterol, Athens, Greece
[3] Sismanoglio Hosp, Microbiol Lab, Athens, Greece
关键词
Colonoscopy; Prostate specific antigen; Prostatic cancer; Screening;
D O I
10.1023/B:UROL.0000034674.19318.86
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction: To evaluate the colonoscopy effects on serum levels of prostate specific antigen (PSA) and PSA ratio. Subjects and methods: Thirty men were studied (median age 68 years, range 32-89). All of them had their serum PSA (total and free) measured 24 hours prior to colonoscopy and also 24 hours, 7 and 30 days after procedure. Results: 14 of 30 (47%) patients, had significantly (p = 0.045) increased Total PSA levels 24 hours after the procedure, 14 (47%) patients had insignificantly (p = 0.139) increased levels 7 days after, while 13 (43%) of them had insignificantly (p = 0,061) increased levels 30 days after colonoscopy. In 7 patients (23%), with total PSA levels in the "gray zone" (4-10 ng/ml) before colonoscopy, a near significant (p = 0.063) raise in PSA ratio was also observed 24 hours after. Conclusion: Flexible colonoscopy affect serum PSA (free and total) levels in certain patients. Special attention must be given to those patients with PSA levels in the "gray zone" before colonoscopy.
引用
收藏
页码:203 / 206
页数:4
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