Isopentenyl diphosphate is the terminal product of the deoxyxylulose-5-phosphate pathway for terpenoid biosynthesis in plants.

被引：36
|
作者：
McCaskill, D [1 ]
Croteau, R [1 ]
机构：
[1] Washington State Univ, Inst Biol Chem, Pullman, WA 99164 USA
来源：
TETRAHEDRON LETTERS | 1999年 / 40卷 / 04期
关键词：
terpenoid biosynthesis; isopentenyl diphosphate isomerase; deoxyxylulose-5-phosphate; isopentenyl diphosphate; dimethylallyl diphosphate; 2-(dimethylamino)ethyl diphosphate;
D O I：
10.1016/S0040-4039(98)02496-4
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Secretory cells specialized for monoterpene biosynthesis via the deoxyxylulose-5-phosphate pathway for terpenoid biosynthesis were isolated from peppermint (Mentha piperita) leaves and used to identify the terminal metabolite of this novel pathway. Incorporation of both [C-13]- and [C-14]pyruvic acid into monoterpenes in the presence of 2-(ditnethylamino)ethyl diphosphate, an inhibitor of isopentenyl diphosphate isomerase, results in accumulation of isopentenyl diphosphate, and not dimethylallyl diphosphate. (C) 1999 Elsevier Science Ltd. All rights reserved.
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收藏
页码：653 / 656
页数：4
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