The bittersweet promise of glycobiology

被引：136

作者：

Dove, A

机构：

来源：

NATURE BIOTECHNOLOGY | 2001年 / 19卷 / 10期

基金：

美国国家卫生研究院;

关键词：

Glycobiology;

D O I：

10.1038/nbt1001-913

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Carbohydrates play a wide range of important roles in the body and, despite the challenges posed by glycobiology, are now tempting targets for drug developers.

引用

页码：913 / 917

页数：5

共 4 条

[1] Structure, mechanism and engineering of a nucleotidylyltransferase as a first step toward glycorandomization [J].

Barton, WA ;

Lesniak, J ;

Biggins, JB ;

Jeffrey, PD ;

Jiang, JQ ;

Rajashankar, KR ;

Thorson, JS ;

Nikolov, DB .

NATURE STRUCTURAL BIOLOGY, 2001, 8 (06) :545-551

[2] Automated solid-phase synthesis of oligosaccharides [J].

Plante, OJ ;

Palmacci, ER ;

Seeberger, PH .

SCIENCE, 2001, 291 (5508) :1523-1527

[3] Engineering Chinese hamster ovary cells to maximize sialic acid content of recombinant glycoproteins [J].

Weikert, S ;

Papac, D ;

Briggs, J ;

Cowfer, D ;

Tom, S ;

Gawlitzek, M ;

Lofgren, J ;

Mehta, S ;

Chisholm, V ;

Modi, N ;

Eppler, S ;

Carroll, K ;

Chamow, S ;

Peers, D ;

Berman, P ;

Krummen, L .

NATURE BIOTECHNOLOGY, 1999, 17 (11) :1116-1121

[4] Imino sugars inhibit the formation and secretion of bovine viral diarrhea virus, a pestivirus model of hepatitis C virus:: Implications for the development of broad spectrum anti-hepatitis virus agents [J].

Zitzmann, N ;

Mehta, AS ;

Carrouée, S ;

Butters, TD ;

Platt, FM ;

McCauley, J ;

Blumberg, BS ;

Dwek, RA ;

Block, TM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (21) :11878-11882

← 1 →