The mechanism of pulmonary hypertension in rats with high-altitude hypoxia

被引：0

作者：

Mazhbich, BI

Nepomnyashchikh, LM

Lushnikova, EL

机构：

[1] RUSSIAN ACAD MED SCI,INST PHYSIOL,MOSCOW 109801,RUSSIA

[2] RUSSIAN ACAD MED SCI,INST REG PATHOL & PATHOMORPHOL,NOVOSIBIRSK,RUSSIA

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 1996年 / 121卷 / 03期

关键词：

high-altitude; pulmonary vessels; pulmonary hypertension; vascular resistance;

D O I：

10.1007/BF02446776

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Morphofunctional examinations of the lungs of rats exposed to high-altitude conditions for 3 to 300 days revealed that systolic pulmonary hypertension observed during the entire period of study is caused by a total increase of the elastic resistance of pulmonary arteries. Adequate bloodflow in such a case is provided by intensive work of the right-ventricular myocardium against this resistance.

引用

页码：296 / 299

页数：4

共 8 条

[1] AN ANALYSIS OF THE PULSATILE HEMODYNAMIC-RESPONSES OF THE PULMONARY CIRCULATION TO ACUTE AND CHRONIC PULMONARY VENOUS HYPERTENSION IN THE AWAKE DOG [J].