Influenza virus hemagglutinin stimulates the protein kinase C activity of human polymorphonuclear leucocytes

被引：27

作者：

Arora, DJS ^{[1
]}

Gasse, N ^{[1
]}

机构：

[1] Univ Quebec, Inst Armand Frappier, Virol Res Ctr, Laval, PQ H7N 4Z3, Canada

来源：

ARCHIVES OF VIROLOGY | 1998年 / 143卷 / 10期

关键词：

D O I：

10.1007/s007050050439

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Human polymorphonuclear leukocytes (PMNL) incubated with influenza virus, A/USSR/90/77 (H1N1) or its hemagglutinin produced a significant increase in their PKC activity when compared with untreated PMNL. The activated kinase translocated from cytosol to cellular membrane. The calcium-dependent enzyme activity was inhibited by a specific inhibitor suggesting that alpha and/or beta isoforms of PKC were involved.

引用

页码：2029 / 2037

页数：9

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