New porphyrazine macrocycles with high viscosity-sensitive fluorescence parameters

被引：24

作者：

Lermontova, S. A. ^{[1
]}

Grigoryev, I. S. ^{[2
]}

Shilyagina, N. Yu. ^{[1
]}

Peskova, N. N. ^{[1
]}

Balalaeva, I. V. ^{[1
]}

Shirmanova, M. V. ^{[3
]}

Klapshina, L. G. ^{[2
]}

机构：

[1] Lobachevsky State Univ Nizhny Novgorod, Nizhnii Novgorod, Russia

[2] Russian Acad Sci, Razuvaev Inst Organometall Chem, Ul Tropinina 49, Nizhnii Novgorod 603137, Russia

[3] Nizhny Novgorod State Med Acad, Nizhnii Novgorod, Russia

来源：

RUSSIAN JOURNAL OF GENERAL CHEMISTRY | 2016年 / 86卷 / 06期

基金：

俄罗斯基础研究基金会;

关键词：

porphyrazine; fluorescence; photodynamic therapy; viscosity; molecular rotor; PHOTODYNAMIC THERAPY; TCNE;

D O I：

10.1134/S1070363216060189

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

New tetraaryltetracyanoporphyrazines have been obtained in the form of metal complexes and free bases via template assembly of a variety of aryltricyanoethylenes as structural units of the macrocycle, and photophysical properties of the products have been studied. The unique high sensitivity of the fluorescent properties to viscosity has been demonstrated. This property opens the possibility of application of the said compounds as sensors of local viscosity. The prepared macrocycles exhibit significant photocytotoxicity, and can be thus used as sensitizers of photodynamic therapy.

引用

页码：1330 / 1338

页数：9

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