Prevention and control of type 2 diabetes by Mediterranean diet: A systematic review

被引:141
作者
Esposito, Katherine [1 ]
Maiorino, Maria Ida [1 ]
Ceriello, Antonio [2 ]
Giugliano, Dario [1 ]
机构
[1] Univ Naples 2, Dept Geriatr & Metab Dis, I-80138 Naples, Italy
[2] IDIBAPS, Barcelona, AC, Spain
关键词
Mediterranean diet; Type; 2; diabetes; Prevention; Glycaemic control; Cardiovascular risk; CARDIOVASCULAR RISK-FACTORS; MYOCARDIAL-INFARCTION; STYLE DIET; LOW-FAT; ADHERENCE; PATTERN; CARBOHYDRATE; EPIDEMIOLOGY; MORTALITY; DISEASE;
D O I
10.1016/j.diabres.2010.04.019
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
We conducted a systematic review of the available studies that assessed the effect of a Mediterranean diet in type 2 diabetes. We searched publications up to 30 November 2009. Seventeen studies were included. Two large prospective studies report a substantially lower risk (83% and 35%, respectively) of type 2 diabetes in healthy people or in post-infarct patients with the highest adherence to a Mediterranean diet. Five randomized controlled trials have evaluated the effects of a Mediterranean diet, as compared with other commonly used diets, on indices of glycaemic control in subjects with type 2 diabetes. Improvement of fasting glucose and HbA1c levels was greater with a Mediterranean diet and ranged from 7 to 40 mg/dl for fasting glucose, and from 0.1 to 0.6% for HbA1c. No trial reported worsening of glycaemic control with a Mediterranean diet. Two controlled trials in a secondary prevention setting demonstrated that post-infarct patients, including diabetic patients, had cardiovascular benefits from a Mediterranean diet. The evidence so far accumulated suggests that adopting a Mediterranean diet may help prevent type 2 diabetes, and also improve glycaemic control and cardiovascular risk in persons with established diabetes. (C) 2010 Elsevier Ireland Ltd. All rights reserved.
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页码:97 / 102
页数:6
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