Psychosis in Parkinson's Disease

被引:1
作者
Remz, Matthew [1 ]
Salinas, Meagen [1 ]
机构
[1] Univ Texas Southwestern Med Ctr Dallas, Dept Neurol & Neurotherapeut, 5323 Harry Hines Blvd, Dallas, TX 75390 USA
关键词
DRUG-INDUCED PSYCHOSIS; VISUAL HALLUCINATIONS; RISPERIDONE TREATMENT; CLOZAPINE; SYMPTOMS; ZIPRASIDONE; OLANZAPINE; PHENOMENOLOGY; ARIPIPRAZOLE; RIVASTIGMINE;
D O I
10.3928/00485713-20200210-02
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Clinically defined by consensus in 2007, Parkinson's disease psychosis (PDP) encompasses psychiatric symptoms of illusions, hallucinations, and delusions associated with Parkinson's disease. Since that time, an increase in research has yielded new insights into clinical features of PDP, how these symptoms evolve over time, and novel therapeutic targets. This article reviews the literature surrounding PDP, highlighting the spectrum of clinical manifestations, the pathophysiology, and treatment options. The article concludes with a treatment strategy incorporating the reviewed evidence.
引用
收藏
页码:112 / 119
页数:8
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[41]   CBT for psychosis in Parkinson's disease: A framework for how and why [J].
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[49]   Pimavanserin for the treatment of Parkinson's disease psychosis: number needed to treat, number needed to harm, and likelihood to be helped or harmed [J].
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