Two new sesquiterpenes from cultures of the fungus Irpex lacteus

被引：1
|
作者：
Ding, Jian-Hai [1 ]
Li, Zheng-Hui [2 ]
Feng, Tao [2 ]
Liu, Ji-Kai [2 ]
机构：
[1] Ningxia Normal Univ, Engn & Technol Res Ctr Liupanshan Resources, Coll Chem & Chem Engn, Guyuan 756000, Peoples R China
[2] South Cent Univ Nationalities, Sch Pharmaceut Sci, Wuhan 430074, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2021年 / 23卷 / 04期
基金：
中国国家自然科学基金;
关键词：
Irpex lacteus; fugnus; secondary metabolite; tremulane sesquiterpene; TREMULANE SESQUITERPENES;
D O I：
10.1080/10286020.2020.1737857
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Two new tremulane-type sesquiterpenes, irlactin L (1) and irlactin M (2) were isolated from cultures of the fungus Irpex lacteus, together with one known compound, 6-hydroxy-2,6-dimethyloct-7-enoic acid (3). Their structures were elucidated by spectroscopic data analysis. Compounds 1-2 were tested for their cytotoxicities against five human cancer cell lines and for their inhibitory activities against isozymes of 11 beta-hydroxysteroid dehydrogenases (11 beta-HSD).
引用
收藏
页码：348 / 352
页数：5
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