The cost-effectiveness of HPV vaccination in addition to screening: a Dutch perspective

被引：12
作者：
Setiawan, Didik [1 ,2 ]
Luttjeboer, Jos [1 ]
Westra, Tjalke Arend [1 ]
Wilschut, Jan C. [3 ]
Suwantika, Auliya A. [1 ,4 ]
Daemen, Toos [3 ]
Atthobari, Jarir [5 ]
Wilffert, Bob [6 ]
Postma, Maarten J. [1 ,7 ]
机构：
[1] Univ Groningen, Dept Pharm, Unit PharmacoEpidemiol & Pharmacoecon PE2, Groningen, Netherlands
[2] Univ Muhammadiyah Purwokerto, Fac Pharm, Purwokerto, Indonesia
[3] Univ Groningen, Univ Med Ctr Groningen, Dept Med Microbiol, Groningen, Netherlands
[4] Padjadjaran State Univ, Fac Pharm, Bandung, Indonesia
[5] Gadjah Mada Univ, Fac Med, Dept Pharmacol & Therapy, Yogyakarta, Indonesia
[6] Univ Groningen, Dept Pharm, Unit Pharmacotherapy & Pharmaceut Care, Groningen, Netherlands
[7] Univ Groningen, Univ Med Ctr Groningen, Dept Epidemiol, Groningen, Netherlands
来源：
EXPERT REVIEW OF VACCINES | 2015年 / 14卷 / 04期
关键词：
cervical cancer; cervical cancer screening; cost-effectiveness; HPV vaccination; The Netherlands; HUMAN-PAPILLOMAVIRUS VACCINATION; HPV-16/18 AS04-ADJUVANTED VACCINE; PREVENT CERVICAL-CANCER; OF-STUDY ANALYSIS; ECONOMIC-EVALUATION; DOUBLE-BLIND; HPV16/18; VACCINATION; CROSS-PROTECTION; QUADRIVALENT; HEALTH;
D O I：
10.1586/14760584.2014.990386
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Addition of the HPV vaccine to available cytological screening has been proposed to increase HPV-related cancer prevention. A comprehensive review on this combined strategy implemented in the Netherlands is lacking. For this review, we therefore analyzed all relevant studies on cost-effectiveness of HPV vaccines in combination with cervical screening in the Netherlands. Most of the studies agree that vaccination in pre-sexual-activity periods of life is cost-effective. Based on published sensitivity analyses, the incremental cost-effectiveness ratio was found to be mainly driven by vaccine cost and discount rates. Fewer vaccine doses, inclusion of additional benefits of these vaccines to prevent HPV-related non-cervical cancers and vaccination of males to further reduce the burden of HPV-induced cancers are three relevant options suggested to be investigated in upcoming economic evaluations.
引用
收藏
页码：589 / 604
页数：16
相关论文
共 82 条
[1]   A cost-utility analysis of cervical cancer vaccination in preadolescent Canadian females [J].
Anonychuk, Andrea M. ;
Bauch, Chris T. ;
Merid, Maraki Fikre ;
Van Kriekinge, Georges ;
Demarteau, Nadia .
BMC PUBLIC HEALTH, 2009, 9
[2]  
[Anonymous], 2005, METHODS EC EVALUATIO
[3]  
[Anonymous], DECISION MODELLING F
[4]  
[Anonymous], 2014, Human papillomavirus and related diseases project
[5]  
[Anonymous], STATISTICAL METHODS
[6]  
[Anonymous], 2011, POPULATION SCREENING
[7]  
[Anonymous], 2014, PHARMACOECONOMIC GUI
[8]  
[Anonymous], 2014, INFLATION CONSUMER P
[9]  
[Anonymous], BROAD SPECTRUM HPV H
[10]  
[Anonymous], BMC INFECT DIS
123456789