Syphilis-associated membranous nephropathy successfully treated with amoxicillin

被引：6

作者：

Hazue, Ryo ^{[1
,4
,5
,6
]}

Ueno, Toshiharu ^{[4
,5
]}

Nozaki, Hiroyuki ^{[6
]}

Kinowaki, Keiichi ^{[2
]}

Ohashi, Kenichi ^{[2
,3
]}

Hoshino, Junichi ^{[4
,5
]}

Sawa, Naoki ^{[4
,5
]}

Ubara, Yoshifumi ^{[4
,5
]}

机构：

[1] Kameda Gen Hosp, Rheumatol Dept, Chiba, Japan

[2] Toranomon Gen Hosp, Dept Pathol, Kawasaki, Kanagawa, Japan

[3] Tokyo Med & Dent Univ, Grad Sch Med & Dent Sci, Dept Human Pathol, Tokyo, Japan

[4] Toranomon Gen Hosp, Nephrol Ctr, Kawasaki, Kanagawa, Japan

[5] Toranomon Gen Hosp, Okinaka Mem Inst Med Res, Kawasaki, Kanagawa, Japan

[6] Kawasaki City Hosp, Kawasaki, Kanagawa, Japan

来源：

CLINICAL NEPHROLOGY | 2021年 / 96卷 / 05期

关键词：

syphilis; membranous nephropathy; nephrotic syndrome; GLOMERULONEPHRITIS; SECONDARY; ANTIGEN;

D O I：

10.5414/CN110586

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

A 33-year-old Japanese man with no significant past medical history was admitted to our hospital for evaluation of weight gain and pitting edema. A laboratory test confirmed nephrotic-range proteinuria. Renal biopsy showed subepithelial deposits, and membranous nephropathy (MN) was diagnosed. Closer examination clarified an active syphilis infection. After renal biopsy, we prescribed amoxicillin for 8 weeks to treat the syphilis infection. Three weeks later, the patient's proteinuria dramatically decreased. This case is of interest because syphilis can become a cause of acute-onset MN in younger adults, and the incidence of syphilis is increasing in Japan.

引用

页码：297 / 301

页数：5

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