Increases in BMD correlate with improvements in bone microarchitecture with Teriparatide treatment in postmenopausal women with osteoporosis

被引：66

作者：

Chen, Peiqi

Miller, Paul D.

Recker, Robert

Resch, Heinrich

Rana, Asad

Pavo, Imre

Sipos, Adrien A.

机构：

[1] Eli Lilly & Co, Lilly Res Lab, Indianapolis, IN 46285 USA

[2] Univ Colorado, Hlth Sci Ctr, Dept Med, Denver, CO 80262 USA

[3] Colorado Ctr Bone Res, Denver, CO USA

[4] Creighton Univ, Med Ctr, Osteoporosis Res Ctr, Omaha, NE USA

[5] St Vincents Hosp, Dept Internal Med, Vienna, Austria

来源：

JOURNAL OF BONE AND MINERAL RESEARCH | 2007年 / 22卷 / 08期

关键词：

teriparatide; lumbar spine and femoral neck BMD; bone microarchitecture; histomorphometry; mu CT;

D O I：

10.1359/JBMR.070413

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Increases in BMD are correlated with improvements in 2D and 3D trabecular microarchitecture indices with teriparatide treatment. Therefore, improvements in trabecular bone microarchitecture may be one of the mechanisms to explain how BMD increases improve bone strength during teriparatide treatment.

引用

收藏

页码：1173 / 1180

页数：8

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