A case report of a patient with rheumatoid arthritis complicated with Mycobacterium avium during tocilizumab treatment

被引：11
作者：
Nakahara, Hideko [1 ]
Kamide, Yosuke [1 ,2 ]
Hamano, Yoshimasa
Hosokawa, Takashi [1 ]
Nishide, Masayuki [1 ]
Lin, Yu [1 ]
Kawamoto, Keisuke [1 ]
Fusama, Mie [3 ]
Higa, Shinji [1 ]
Kuroiwa, Takashi [4 ]
Igarashi, Tsuyoshi [1 ]
Kuritani, Taro [1 ]
Maeda, Keiji [1 ]
机构：
[1] NTT W Osaka Hosp, Div Allergy Rheumatol & Connect Tissue Dis, Dept Internal Med, Tennoji Ku, Osaka 5438922, Japan
[2] Gunma Univ, Grad Sch Med, Dept Med & Mol Sci, Maebashi, Gunma 3718511, Japan
[3] NTT W Osaka Hosp, Div Nursing, Osaka 5438922, Japan
[4] Gunma Univ, Grad Sch Med, Dept Med & Clin Sci, Maebashi, Gunma 3718511, Japan
来源：
MODERN RHEUMATOLOGY | 2011年 / 21卷 / 06期
关键词：
Anti-IL-6 receptor antibody; Biologics; IL-6; MAC; TNF alpha; TUMOR-NECROSIS-FACTOR; COMPLEX INFECTION; INTERFERON-GAMMA; FACTOR-ALPHA; POSTMARKETING SURVEILLANCE; JAPANESE PATIENTS; IFN-GAMMA; TUBERCULOSIS; MONOTHERAPY; INFLIXIMAB;
D O I：
10.1007/s10165-011-0448-1
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
A female patient with rheumatoid arthritis (RA) suffered from Mycobacterium avium (M. avium) infection during tocilizumab treatment. Tocilizumab was discontinued and she was treated with a recommended chemotherapy, resulting in improvement of M. avium. Tocilizumab retreatment did not aggravate M. avium infection, and radiographic abnormalities improved over 1 year after cessation of the recommended therapy. Tocilizumab may be one candidate for intractable RA patients with M. avium if any biologic is required.
引用
收藏
页码：655 / 659
页数：5
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