The appropriate Surgical strategy for patients with combined carotid and corollary artery disease remains controversial. We retrospectively compared our surgical results for 2 types of approaches in this disorder. The records of 76 patients Consecutively operated oil for carotid and corollary artery disease between August 1993 and October 2004 were reviewed. There were IS males (66.6%) and 9 females (33.3%) in group I. Group II consisted of 35 males (71.4%) and 14 females (28.5%). The patients were divided into two groups: patients with combined off-pump corollary artery bypass and carotid endarterectomy (group I, n = 27), and those with one-stage on-pump corollary artery bypass and carotid endarterectomy (group 11, it = 49). Surgical mortality and morbidity and late Outcome were compared among the two groups. The average number of grafts was 1.2 +/- 0.4, with the average operative time of 3.3 +/- 0.3 hours in group I, and 2.3 +/- 0.5 grafts with operative time of 4.6 +/- 0.4 hours in group II (P < 0.00 1 and P < 0.00 1, respectively). There was I death (3.7%) in group I and 2 deaths (4.8%) in group 11 (P = 0.937). No patient from either group I or group II had postoperative stroke. Mean hospital stay was 7.4 +/- 1.9 days in 01-OLIP I and 11.3 +/1 1.7 days in group II (P < 0.001). At a mean follow-up of 5.5 +/- 3.3 years in group 1, 1 patient had contralateral carotid endarterectomy (3.7%). Group II had a mean follow-up of 5.2 +/- 3.0 years and contralateral carotid endarterectomy was performed in I patient (2.0%). There were no late strokes or deaths in either group. Combined corollary artery bypass grafting and carotid endarterectomy using 2 different types of technique is a safe and effective procedure in patients with significant concornitant nionolateral carotid and corollary artery disease.