Lens and retina regeneration: transdifferentiation, stem cells and clinical applications

被引：103
作者：
Tsonis, PA [1 ]
Del Rio-Tsonis, K
机构：
[1] Univ Dayton, Mol Biol Lab, Dept Biol, Dayton, OH 45469 USA
[2] Miami Univ, Dept Zool, Oxford, OH 45056 USA
来源：
EXPERIMENTAL EYE RESEARCH | 2004年 / 78卷 / 02期
关键词：
eye; lens; retina; regeneration; transdifferentiation; stem cells; cataracts; retinal diseases;
D O I：
10.1016/j.exer.2003.10.022
中图分类号：
R77 [眼科学];
学科分类号：
100212 ;
摘要：
In this review we present a synthesis on the potential of vertebrate eye tissue regeneration, such as lens and retina. Particular emphasis is given to two different strategies used for regeneration, transdifferentiation and stem cells. Similarities and differences between these two strategies are outlined and it is proposed that both strategies might follow common pathways. Furthermore, we elaborate on specific clinical applications as the outcome of regeneration-based research (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：161 / 172
页数：12
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