Synthesis of pyrrolo[2,3-b]quinoxalines by the Pd/C-catalyzed multicomponent reaction of 1,2-dichloroquinoxaline with hydrazine hydrate, phenylacetylene, and a variety of aldehydes in water

被引：32

作者：

Bakherad, Mohammad ^{[1
]}

Keivanloo, Ali ^{[1
]}

Jajarmi, Saeideh ^{[1
]}

机构：

[1] Shahrood Univ Technol, Sch Chem, Shahrood, Iran

来源：

TETRAHEDRON | 2012年 / 68卷 / 09期

关键词：

Pyrroloquinoxaline; Sonogashira reaction; Palladium catalyzed; Aldehydes; ONE-POT SYNTHESIS; 5-HT3 RECEPTOR AGONISTS; VARICELLA-ZOSTER-VIRUS; 2-SUBSTITUTED INDOLES; BIOLOGICAL EVALUATION; SELECTIVE-INHIBITION; FACILE SYNTHESIS; HIGHLY POTENT; ARYL HALIDES; DERIVATIVES;

D O I：

10.1016/j.tet.2012.01.045

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The one-pot, Pd/C-catalyzed, multicomponent reaction of 1,2-dichloroquinoxaline with hydrazine hydrate, phenylacetylene, and a variety of aldehydes provides an efficient and direct method for the preparation of N-substituted pyrrolo[2,3-b]quinoxalines in water at 70 degrees C. (C) 2012 Elsevier Ltd. All rights reserved.

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页码：2107 / 2112

页数：6

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