Physical exercise as adjuvant therapy for patients undergoing hematopoietic stem cell transplantation

被引:119
作者
Wiskemann, J. [1 ,2 ]
Huber, G. [2 ]
机构
[1] Heidelberg Univ, Dept Psychosomat Med & Psychotherapy, Cent Inst Mental Hlth, Med Dept Mannheim, D-68159 Mannheim, Germany
[2] Heidelberg Univ, Inst Sports & Sport Sci, D-68159 Mannheim, Germany
关键词
physical exercise; cancer; hematopoietic stem cell transplantation; intervention studies;
D O I
10.1038/sj.bmt.1705917
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Even when the procedures are successful, patients experience considerable physical, psychological and psychosocial stress before, during and after hematopoietic stem cell transplantation ( HSCT). Physical exercise therapy constitutes a potentially promising intervention to reduce such stress within the framework of HSCT because of its multidimensional effectiveness. Up to May 2007, fifteen published studies have examined physical exercise interventions in the context of HSCT, with no study reporting any unexpected or negative effects. The most common intervention involved isolated aerobic exercise programs and occurred during or after the transplantation process; strength training programs and combined intervention strategies are being examined more rarely. Significant benefits from the exercise interventions have been predominantly reported for physical performance, quality of life and fatigue status of the patients. Several other benefits like a faster recurrence of immune cells or reduced severity of therapy-related side effects can be estimated. Future research is needed for the purpose of evidence-based medicine/ therapy to provide more rigorous examinations of these interventions, to address existing methodological problems and to identify further effect levels of physical exercise therapy in the context of HSCT.
引用
收藏
页码:321 / 329
页数:9
相关论文
共 67 条
[1]  
[Anonymous], 1999, Hematopoietic stem cell transplantation
[2]   Reintegration after bone marrow transplantation [J].
Baker, F ;
Zabora, J ;
Polland, A ;
Wingard, J .
CANCER PRACTICE, 1999, 7 (04) :190-197
[3]   Psychological distress among adult patients being evaluated for bone marrow transplantation [J].
Baker, F ;
Marcellus, D ;
Zabora, J ;
Polland, A ;
Jodrey, D .
PSYCHOSOMATICS, 1997, 38 (01) :10-19
[4]  
Baumann FT., 2005, DTSCH Z ONKOLOGIE, V37, P152, DOI [10.1055/s-2005-918019, DOI 10.1055/S-2005-918019]
[5]   Self-efficacy and adjustment in cancer patients: A preliminary report [J].
Beckham, JC ;
Burker, EJ ;
Lytle, BL ;
Feldman, ME ;
Costakis, MJ .
BEHAVIORAL MEDICINE, 1997, 23 (03) :138-142
[6]   Individualized exercise program for the treatment of severe fatigue in patients after allogeneic hematopoietic stem-cell transplant: a pilot study [J].
Carlson, LE ;
Smith, D ;
Russell, J ;
Fibich, C ;
Whittaker, T .
BONE MARROW TRANSPLANTATION, 2006, 37 (10) :945-954
[7]   Feasibility of exercise during treatment for multiple myeloma [J].
Coleman, EA ;
Coon, S ;
Hall-Barrow, J ;
Richards, K ;
Gaylor, D ;
Stewart, B .
CANCER NURSING, 2003, 26 (05) :410-419
[8]  
Coleman Elizabeth Ann, 2003, Clin J Oncol Nurs, V7, P529, DOI 10.1188/03.CJON.529-534
[9]   Keep moving: Patients with myeloma talk about exercise and fatigue [J].
Coon, SK ;
Coleman, EA .
ONCOLOGY NURSING FORUM, 2004, 31 (06) :1127-1135
[10]  
Courneya KS, 2000, PSYCHO-ONCOLOGY, V9, P127, DOI 10.1002/(SICI)1099-1611(200003/04)9:2<127::AID-PON438>3.0.CO