The oral cavity Crohn's disease

被引:79
作者
Pittock, S
Drumm, B
Fleming, P
McDermott, M
Imrie, C
Flint, S
Bourke, B [1 ]
机构
[1] Our Ladys Hosp Sick Children, Childrens Res Ctr, Dublin 12, Ireland
[2] Univ Coll Dublin, Conway Inst Biomol & Biomed Sci, Dept Pediat, Dublin 2, Ireland
[3] Trinity Coll Dublin, Dublin Dent Hosp, Dept Oral Med, Dublin 2, Ireland
关键词
D O I
10.1067/mpd.2001.113008
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
We assessed the utility of expert or al examination as a part of the diagnostic evaluation of patients with suspected Crohn's disease. Of 45 patients with newly diagnosed CD, 25 had been examined by a dentist. Twelve (48%) of these had oral CD lesions. Mucosal tags constituted the most frequent form of oral lesion (8/12). Of 8 oral biopsy specimens, 6 (75%) contained non-caseating granulomas. Patients with oral CD had more oral symptoms, presented for diagnosis sooner, and were more likely to have other upper gastrointestinal inflammation than those without oral lesions. Oral manifestations of CD are common in children; therefore, expert oral examination may be useful during diagnostic evaluation of children with suspected inflammatory bowel disease.
引用
收藏
页码:767 / 771
页数:5
相关论文
共 16 条
[1]  
BARNARD KM, 1994, J DENT RES, V73, pA388
[2]  
BASU MK, 1975, GUT, V16, P249
[3]  
BASU MK, 1980, CLIN GASTROENTEROL, V9, P307
[4]  
BORAZ RA, 1988, J DENT CHILD, V55, P72
[5]  
Challacombe S J, 1997, Oral Dis, V3, P127
[6]   ANALYSIS OF RELIABILITY OF DETECTION AND DIAGNOSTIC VALUE OF VARIOUS PATHOLOGICAL FEATURES IN CROHNS-DISEASE AND ULCERATIVE-COLITIS [J].
COOK, MG ;
DIXON, MF .
GUT, 1973, 14 (04) :255-262
[7]   Long-term evolution of oral localization of Crohn's disease [J].
Cosnes, A ;
Dupuy, A ;
Revuz, J ;
Delchier, JC ;
Contou, JF ;
Gendre, JP ;
Cosnes, J .
GASTROENTEROLOGY, 1998, 114 (04) :A956-A956
[8]   EXTRA-INTESTINAL COMPLICATIONS OF CROHNS-DISEASE AND ULCERATIVE-COLITIS - STUDY OF 700 PATIENTS [J].
GREENSTEIN, AJ ;
JANOWITZ, HD ;
SACHAR, DB .
MEDICINE, 1976, 55 (05) :401-412
[9]   ORAL FINDINGS IN PATIENTS WITH ACTIVE OR INACTIVE CROHNS-DISEASE [J].
HALME, L ;
MEURMAN, JH ;
LAINE, P ;
VONSMITTEN, K ;
SYRJANEN, S ;
LINDQVIST, C ;
STRANDPETTINEN, I .
ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY, 1993, 76 (02) :175-181
[10]   EXTRAINTESTINAL MANIFESTATIONS OF INFLAMMATORY BOWEL-DISEASE IN CHILDREN [J].
HYAMS, JS .
JOURNAL OF PEDIATRIC GASTROENTEROLOGY AND NUTRITION, 1994, 19 (01) :7-21