Successful treatment of ptyalism gravidarum with clonidine hydrochloride: A case report

被引：1

作者：

De Braga, Victoria ^{[1
]}

Dahdouh, Elias M. ^{[2
]}

Balayla, Jacques ^{[3
]}

机构：

[1] McGill Univ, Fac Med, 3605 Rue Montagne, Montreal, PQ H3G 2M1, Canada

[2] CHU St Justine, Assisted Reprod Technol Ctr, Dept Obstet & Gynecol, 3175 Chem Cote St Catherine, Montreal, PQ H3T 1C5, Canada

[3] McGill Univ, Dept Obstet & Gynecol, 3605 Rue Montagne, Montreal, PQ H3G 2M1, Canada

来源：

CASE REPORTS IN WOMENS HEALTH | 2022年 / 34卷

关键词：

Ptyalism gravidarum; Clonidine hydrochloride; Sialorrhea; Pregnancy; Case report; BOTULINUM-TOXIN-A; PREGNANCY;

D O I：

10.1016/j.crwh.2022.e00409

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Ptyalism gravidarum is a disorder characterized by significant hypersalivation during pregnancy, which affects and interferes with quality of life. No published data has demonstrated an effective approach to treat this condition. This case study reports the use of clonidine hydrochloride, an alpha-2-adrenergic receptor agonist that is typically used as an anti-hypertensive agent, to treat the excessive sialorrhea typical of this disorder. The patient who was treated with this medication saw significant improvement in her symptoms and did not experience any subsequent adverse effects throughout her pregnancy. As a result, we believe that further investigation into this potential treatment for ptyalism gravidarum is necessary ahead of medical guideline incorporation and clinical implementation.

引用

页数：3

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