The role of imaging and molecular imaging in the early detection of metabolic and cardiovascular dysfunctions

被引：3
|
作者：
Montet-Abou, K. [2 ]
Viallon, M. [2 ]
Hyacinthe, J-N [2 ]
Delattre, B. [2 ]
Vallee, J-P [2 ]
Didier, D. [2 ]
Croisille, P. [3 ]
Montet, X. [1 ,2 ]
机构：
[1] Univ Geneva, Cell Physiol & Metab Dept, CH-1211 Geneva 14, Switzerland
[2] Univ Hosp Geneva, Dept Radiol, Geneva, Switzerland
[3] Hosp Civils Lyon, Hop Louis Pradel, Dept Radiol, Lyon, France
来源：
INTERNATIONAL JOURNAL OF OBESITY | 2010年 / 34卷
基金：
瑞士国家科学基金会;
关键词：
MRI; molecular imaging; inflammation; heart; cardiovascular diseases; CORONARY-ARTERY-DISEASE; ULTRASMALL SUPERPARAMAGNETIC PARTICLES; MYOCARDIAL TRIGLYCERIDE CONTENT; PERFUSED RAT-HEART; GD-DTPA INJECTION; MAGNETIC-RESONANCE; IN-VIVO; DELAYED-ENHANCEMENT; IRON-OXIDE; CONTRAST AGENT;
D O I：
10.1038/ijo.2010.242
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Despite intense effort, obesity is still rising throughout the world. Links between obesity and cardiovascular diseases are now well established. Most of the cardiovascular changes related to obesity can be followed by magnetic resonance imaging (MRI) or by magnetic resonance spectroscopy (MRS). In particular, we will see in this review that MRI/MRS is extremely well suited to depict (1) changes in cardiac mass and function, (2) changes in stroke volume, (3) accumulation of fat inside the mediastinum or even inside the cardiomyocytes, (4) cell viability and (5) molecular changes during early cardiovascular diseases. International Journal of Obesity (2010) 34, S67-S81; doi:10.1038/ijo.2010.242
引用
收藏
页码：S67 / S81
页数：15
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