A novel method of luteal supplementation with recombinant luteinizing hormone when a gonadotropin-releasing hormone agonist is used instead of human chorionic gonadotropin for ovulation triggering: a randomized prospective proof of concept study

被引：89
作者：
Papanikolaou, Evangelos G. [1 ,2 ]
Verpoest, Willem [1 ]
Fatemi, Human [1 ]
Tarlatzis, Basil [2 ]
Devroey, Paul [1 ]
Tournaye, Herman [1 ]
机构：
[1] Vrije Univ Brussel, Univ Ziekenhuis Brussel, Ctr Reprod Med, Brussels, Belgium
[2] Aristotle Univ Thessaloniki, Dept Obstet & Gynecol 1, Assisted Reprod Unit, GR-54006 Thessaloniki, Greece
来源：
FERTILITY AND STERILITY | 2011年 / 95卷 / 03期
关键词：
Recombinant LH; agonist triggering; pregnancy; OHSS; GnRH-antagonist; FINAL OOCYTE MATURATION; OVARIAN HYPERSTIMULATION SYNDROME; GNRH AGONIST; ANTAGONIST; CYCLES; PHASE; HCG; COTREATMENT; RESCUE; WOMEN;
D O I：
10.1016/j.fertnstert.2010.09.023
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
This pilot study investigates the role of luteal supplementation with recombinant LH in an attempt to reverse the poor reproductive outcome previously noticed after GnRH-agonist triggering of final oocyte maturation for IVF. Similar implantation rates were achieved with the novel recombinant LH luteal supplementation scheme compared with the standard luteal P protocol (25.0% vs. 26.7%, respectively). No cases of ovarian hyperstimulation syndrome (OHSS) were noticed in either group. (Fertil Steril (R) 2011;95:1174-7. (C) 2011 by American Society for Reproductive Medicine.)
引用
收藏
页码：1174 / 1177
页数：4
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