Antibodies reacting to carbonic anhydrase isozymes (I and II) and albumin in sera from dogs

被引：0

作者：

Nishita, Toshiho ^{[1
]}

Miyazaki, Rui ^{[1
]}

Miyazaki, Takae ^{[1
]}

Ochiai, Hideharu ^{[2
]}

Orito, Kensuke ^{[3
]}

机构：

[1] Azabu Univ, Sch Vet Med, Lab Physiol 1, 1-17-71 Fuchinobe, Sagamihara, Kanagawa 2525201, Japan

[2] Azabu Univ, Sch Vet Med, Res Inst Biosci, 1-17-71 Fuchinobe, Sagamihara, Kanagawa 2525201, Japan

[3] Azabu Univ, Sch Vet Med, Lab Physiol 2, 1-17-71 Fuchinobe, Sagamihara, Kanagawa 2525201, Japan

来源：

RESEARCH IN VETERINARY SCIENCE | 2016年 / 106卷

关键词：

Antibody; Bovine serum albumin; Carbonic anhydrase; Dog; Food allergy; SJOGRENS-SYNDROME; INDUCTION; IGG;

D O I：

10.1016/j.rvsc.2016.04.010

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

IgGs to carbonic anhydrase isozymes (CA-I and CA-II) and albumin were identified in dog serum. IgG titers were determined in the sera of asymptomatic dogs, and in dogs with atopic dermatitis, diarrhea and/or vomiting, diabetes and/or pancreatitis, kidney disease, hepatic disease, and thyroid gland disease, using ELISA. Low titres of IgG-reactive CA-I, CA-II, BSA, and CSA were found in the sera of healthy beagles. Compared with healthy beagles, there was a significant difference in the titers of antibodies against CA-I in asymptomatic dogs, dogs with diabetes and/or pancreatitis, or thyroid gland disease, or hepatic disease. Compared with healthy beagles, there was a significant difference in the antibody titer of anti-CA-II IgG in asymptomatic dogs and in those with hepatic disease. There was a significant difference in the antibody titer of anti-BSA IgG between healthy beagles and dogs with hepatic disease. (C) 2016 Elsevier Ltd. All rights reserved.

引用

页码：180 / 182

页数：3

共 14 条

[1]

Andoh A, 2002, INT J MOL MED, V9, P499

[2] Antibodies to carbonic anhydrase in endometriosis: Prevalence, specificity, and relationship to clinical and laboratory parameters [J].

DCruz, OJ ;

Wild, RA ;

Haas, GG ;

Reichlin, M .

FERTILITY AND STERILITY, 1996, 66 (04) :547-556

[3]

Guilford W. G., 1996, Strombeck's small animal gastroenterology, by W. G. Guilford et al., P436

[4]

Halliwell R.E.W., 2006, ADV VET DEMATOLOGY, V5, P28

[5] Differential binding of IgG and IgA antibodies to antigenic determinants of bovine serum albumin [J].

Hilger, C ;

Grigioni, F ;

De Beaufort, C ;

Michel, G ;

Freilinger, J ;

Hentges, F .

CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2001, 123 (03) :387-394

[6]

INAGAKI Y, 1991, Journal of Dermatological Science, V2, P147, DOI 10.1016/0923-1811(91)90060-B

[7] ANTIBODIES TO CARBONIC-ANHYDRASE IN SYSTEMIC LUPUS-ERYTHEMATOSUS AND OTHER RHEUMATIC DISEASES [J].

ITOH, Y ;

REICHLIN, M .

ARTHRITIS AND RHEUMATISM, 1992, 35 (01) :73-82

[8] Evolutionary distance from human homologs reflects allergenicity of animal food proteins [J].

Jenkins, John A. ;

Breiteneder, Heimo ;

Mills, E. N. Clare .

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2007, 120 (06) :1399-1405

[9] Serum antibodies to carbonic anhydrase I and II in patients with idiopathic chronic pancreatitis and Sjogren's syndrome [J].

KinoOhsaki, J ;

Nishimori, I ;

Morita, M ;

Okazaki, K ;

Yamamoto, Y ;

Onishi, S ;

Hollingsworth, MA .

GASTROENTEROLOGY, 1996, 110 (05) :1579-1586

[10]

NISHIMORI I, 1995, J IMMUNOL, V154, P4865

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