Nepafenac-associated corneal melt

被引：48

作者：

Wolf, Eric Jay ^{[1
]}

Kleiman, Lynda Z. ^{[1
]}

Schrier, Amilia ^{[1
]}

机构：

[1] Columbia Univ Coll Phys & Surg, Dept Ophthalmol, Edward S Harkness Eye Inst, New York, NY 10032 USA

来源：

JOURNAL OF CATARACT AND REFRACTIVE SURGERY | 2007年 / 33卷 / 11期

关键词：

D O I：

10.1016/j.jcrs.2007.06.043

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

We describe a patient with systemic graft-versus-host disease who developed a nonhealing epithelial defect after cataract surgery that healed on cessation of a topical nonsteroidal antiinflammatory drug (NSAID) (ketorolac). The patient developed a central corneal perforation in the fellow eye while on a new NSAID formulation (nepafenac) after routine cataract surgery. Our case suggests that new topical NSAIDs may be similar to older NSAID formulations in promoting corneal melting in patients predisposed to poor epithelialization and corneal wound healing.

引用

页码：1974 / 1975

页数：2

共 3 条

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OPHTHALMOLOGY, 2001, 108 (05) :936-944

[3] Corneal ulceration and perforation with ketorolac tromethamine (Acular®) use after PRK [J].

Mian, SI ;

Gupta, A ;

Pineda, R .

CORNEA, 2006, 25 (02) :232-234

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