An efficient and facile procedure for the synthesis of 4,6-diaryl-2(1H)-pyridones under solvent-free conditions

被引：19

作者：

Rong, Liangce ^{[1
]}

Wang, Haiying ^{[1
]}

Shi, Jingwen ^{[1
]}

Yang, Fang ^{[1
]}

Yao, Hao ^{[1
]}

Tu, Shuajiang ^{[1
]}

机构：

[1] Xuzhou Normal Univ, Dept Chem, Key Lab Biotechnol Med Plant, Xuzhou 221116, Jiangsu, Peoples R China

来源：

JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 44卷 / 06期

关键词：

D O I：

10.1002/jhet.5570440641

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient and convenient method for the preparation of 4,6-diaryl-2(1H)-pyridones by the one-pot reaction of aromatic aldehydes, aromatic ketones and malononitrile, in the presence of sodium hydroxide under solvent-free condition is reported. This method has the advantages of good yields, mild reaction conditions, easy workup, inexpensive reagents and being environmentally friendly over the existing procedures.

引用

页码：1505 / 1508

页数：4

共 29 条

[1]

AGGARWAL V, 1982, SYNTHESIS-STUTTGART, P214

[2] Regioselective synthesis of 2(1H)-pyridinones from β-aminoenones and malononitrile.: Reaction mechanism [J].