Is primary hepatic angiosarcoma in children an indication for liver transplantation?-A single-centre experience and review of the literature

被引：7

作者：

Alden, Josefin ^{[1
]}

Baecklund, Fredrik ^{[2
]}

Einberg, Afrodite Psaros ^{[3
]}

Casswall, Thomas ^{[3
]}

Wessman, Sandra ^{[4
]}

Ericzon, Bo-Goran ^{[1
]}

Nowak, Greg ^{[1
]}

机构：

[1] Karolinska Univ Hosp Huddinge, Dept Transplantat Surg, Stockholm, Sweden

[2] Karolinska Univ Hosp Solna, Paediat Oncol Unit, Stockholm, Sweden

[3] Karolinska Univ Hosp Huddinge, Dept Paediat Gastroenterol Hepatol & Nutr, Stockholm, Sweden

[4] Karolinska Univ Hosp Solna, Dept Clin Pathol & Cytol, Stockholm, Sweden

来源：

PEDIATRIC TRANSPLANTATION | 2021年 / 25卷 / 08期

关键词：

chemotherapy; liver transplantation; primary hepatic angiosarcoma; HEMANGIOMA;

D O I：

10.1111/petr.14095

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

PHA in the paediatric population is an extremely rare and aggressive malignant soft tissue neoplasm, with less than 50 cases published worldwide. The prognosis is dismal. If the tumour is unresectable, one treatment option is LT. In this article, the current available literature is reviewed and additionally, three cases of paediatric patients with PHA who underwent LT at Karolinska University Hospital, Sweden, are presented. Based on the literature and our own experience, there is undoubtedly possible good outcome of LT due to PHA. On the contrary, no patients have survived PHA without LT. PHA in paediatric patients should be recommended to LT in selected patients. Effect of modern adjuvant chemo and RT should be evaluated further based on international registry for such rare cases of PHA.

引用

页数：10

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