Preparation and characterization of hydroxyapatite-sodium alginate scaffolds by extrusion freeforming

被引：19
作者：
Zhou, Kui [1 ]
Zhang, Xianglin [1 ]
Chen, Zhichao [1 ,2 ]
Shi, Lei [1 ]
Li, Wenchao [1 ]
机构：
[1] Huazhong Univ Sci & Technol, Sch Mat Sci & Engn, State Key Lab Mat Proc & Die & Mould Technol, Wuhan 430074, Peoples R China
[2] Univ Loughborough, Sch Mech & Mfg Engn, Loughborough LE11 3TU, Leics, England
来源：
CERAMICS INTERNATIONAL | 2015年 / 41卷 / 10期
基金：
中国国家自然科学基金;
关键词：
Sintering; Extrusion freeforming; Hydroxyapatite; Sodium alginate; Porous scaffold; POROUS SCAFFOLDS; FABRICATION; ROUGHNESS; POROSITY; CELLS;
D O I：
10.1016/j.ceramint.2015.07.016
中图分类号：
TQ174 [陶瓷工业]; TB3 [工程材料学];
学科分类号：
0805 ; 080502 ;
摘要：
Extrusion freeforming is a facile approach to produce complex 3D structures with controlled architecture and porosity. In this work, a new slurry system, mainly containing hydroxyapatite (HA) and sodium alginate (SA), has been used to fabricate porous hydroxyapatite scaffolds. After cross-linking in 5% calcium chloride (CaCl2) solution for 24 h, HA-SA composite scaffolds were sintered at 1000-1300 degrees C for 2 h. The properties of HA-SA composite scaffolds before and after sintering have been investigated. The new slurry system has greatly improved the quality of porous hydroxyapatite scaffolds. (C) 2015 Elsevier Ltd and Techna Group S.r.l. All rights reserved.
引用
收藏
页码：14029 / 14034
页数：6
相关论文
共 27 条
[1]   The Effect of Exposed Glass Fibers and Particles of Bioactive Glass on the Surface Wettability of Composite Implants [J].
Abdulmajeed, Aous A. ;
Lassila, Lippo V. ;
Vallittu, Pekka K. ;
Narhi, Timo O. .
INTERNATIONAL JOURNAL OF BIOMATERIALS, 2011, 2011
[2]   Relevance of the physicochemical properties of CaO catalysts for the methanolysis of triglycerides to obtain biodiesel [J].
Alonso, D. Martin ;
Vila, F. ;
Mariscal, R. ;
Ojeda, M. ;
Lopez Granados, M. ;
Santamaria-Gonzalez, J. .
CATALYSIS TODAY, 2010, 158 (1-2) :114-120
[3]   Novel fabrication of hierarchically porous hydroxyapatite scaffolds with refined porosity and suitable strength [J].
Chen, Z. C. ;
Zhang, X. L. ;
Zhou, K. ;
Cai, H. ;
Liu, C. Q. .
ADVANCES IN APPLIED CERAMICS, 2015, 114 (03) :183-187
[4]   Rapid prototyping of chitosan-coated alginate scaffolds through the use of a 3D fiber deposition technique [J].
Colosi, Cristina ;
Costantini, Marco ;
Latini, Roberta ;
Ciccarelli, Serena ;
Stampella, Alessandra ;
Barbetta, Andrea ;
Massimi, Mara ;
Devirgiliis, Laura Conti ;
Dentini, Mariella .
JOURNAL OF MATERIALS CHEMISTRY B, 2014, 2 (39) :6779-6791
[5]   Hydroxyapatite surface roughness: Complex modulation of the osteoclastogenesis of human precursor cells [J].
Costa-Rodrigues, Joao ;
Fernandes, Anabela ;
Lopes, Maria A. ;
Fernandes, Maria H. .
ACTA BIOMATERIALIA, 2012, 8 (03) :1137-1145
[6]   Nucleus alignment and cell signaling in fibroblasts: response to a micro-grooved topography [J].
Dalby, MJ ;
Riehle, MO ;
Yarwood, SJ ;
Wilkinson, CDW ;
Curtis, ASG .
EXPERIMENTAL CELL RESEARCH, 2003, 284 (02) :274-282
[7]   Bioprintable, cell-laden silk fibroin-gelatin hydrogel supporting multilineage differentiation of stem cells for fabrication of three-dimensional tissue constructs [J].
Das, Sanskrita ;
Pati, Falguni ;
Choi, Yeong-Jin ;
Rijal, Girdhari ;
Shim, Jin-Hyung ;
Kim, Sung Won ;
Ray, Alok R. ;
Cho, Dong-Woo ;
Ghosh, Sourabh .
ACTA BIOMATERIALIA, 2015, 11 :233-246
[8]   Robocasting of 45S5 bioactive glass scaffolds for bone tissue engineering [J].
Eqtesadi, Siamak ;
Motealleh, Azadeh ;
Miranda, Pedro ;
Pajares, Antonia ;
Lemos, Alexandra ;
Ferreira, Jose M. F. .
JOURNAL OF THE EUROPEAN CERAMIC SOCIETY, 2014, 34 (01) :113-124
[9]   In situ observation of defects in hydroxyapatite up to 1200°C by ultraviolet Raman spectroscopy [J].
Fujimori, H ;
Toya, H ;
Ioku, K ;
Goto, S ;
Yoshimura, M .
CHEMICAL PHYSICS LETTERS, 2000, 325 (04) :383-388
[10]   Microporosity enhances bioactivity of synthetic bone graft substitutes [J].
Hing, KA ;
Annaz, B ;
Saeed, S ;
Revell, PA ;
Buckland, T .
JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE, 2005, 16 (05) :467-475
123