Synthesis of substituted 2H-chromenes catalyzed by lipase immobilized on magnetic multiwalled carbon nanotubes

被引：7

作者：

Liu, Jiaxu ^{[1
]}

Zhao, Wenxin ^{[1
]}

Zhang, Liu ^{[1
]}

Zhang, Min ^{[1
]}

Chen, Yanqiang ^{[1
]}

Xu, You ^{[1
]}

Li, Yinghua ^{[2
]}

Wang, Lei ^{[1
]}

机构：

[1] Jilin Univ, Sch Life Sci, Key Lab Mol Enzymol & Engn, Minist Educ, Changchun 130023, Peoples R China

[2] First Hosp Jilin Univ, Changchun, Peoples R China

来源：

BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY | 2021年 / 68卷 / 02期

关键词：

2H-chromene; enzyme; immobilization; magnetic; multiwalled carbon nanotube; ENZYME IMMOBILIZATION; PROMISCUITY; EFFICIENT; IMPROVEMENT;

D O I：

10.1002/bab.1939

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Porcine pancreas lipase (PPL) was immobilized on magnetic multiwalled carbon nanotubes successfully for the synthesis of substituted 2H-chromenes. The catalytic activity of immobilized PPL was much higher than that of free PPL. Effects of reaction medium, temperature, and enzyme dosage were also investigated. Under optimum reaction conditions (acetylacetone (1 mmol), salicylaldehyde (1 equivalent), methanol (10 equivalent), and immobilized PPL (protein content: 30 mg; 65 degrees C; DMF 5 mL; 5 H), the immobilized PPL showed an excellent catalytic performance on the synthesis of substituted 2H-chromenes. Moreover, the immobilized PPL exhibited satisfactory thermostability, operational simplicity, and reusability in this reaction.

引用

页码：411 / 416

页数：6

共 41 条

[1] SiO2 coated Fe3O4 magnetic nanoparticle dispersed multiwalled carbon nanotubes based amperometric glucose biosensor
Baby, Tessy Theres
Ramaprabhu, S.
[J]. TALANTA, 2010, 80 (05) : 2016 - 2022
[2] Catalytic promiscuity in biocatalysis: Using old enzymes to form new bonds and follow new pathways
Bornscheuer, UT
Kazlauskas, RJ
[J]. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2004, 43 (45) : 6032 - 6040
[3] Hydrolases: catalytically promiscuous enzymes for non-conventional reactions in organic synthesis
Busto, Eduardo
Gotor-Fernandez, Vicente
Gotor, Vicente
[J]. CHEMICAL SOCIETY REVIEWS, 2010, 39 (11) : 4504 - 4523
[4] Two-step desymmetrization of dipyrazolidyl 3-phenylglutarate via lipase-catalyzed hydrolysis in organic solvents
Chan, Po-Hao
Tsai, Shau-Wei
[J]. CHEMICAL ENGINEERING SCIENCE, 2016, 139 : 41 - 48
[5] Nanomaterials for biocatalyst immobilization - state of the art and future trends
Cipolatti, Eliane P.
Valerio, Alexsandra
Henriques, Rosana O.
Moritz, Denise E.
Ninow, Jorge L.
Freire, Denise M. G.
Manoel, Evelin A.
Fernandez-Lafuente, Roberto
de Oliveira, Debora
[J]. RSC ADVANCES, 2016, 6 (106): : 104675 - 104692
[6] Biological importance of structurally diversified chromenes
Costa, Marta
Dias, Tatiana A.
Brito, Alexandra
Proenca, Fernanda
[J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2016, 123 : 487 - 507
[7] Chemical oxidation of multiwalled carbon nanotubes
Datsyuk, V.
Kalyva, M.
Papagelis, K.
Parthenios, J.
Tasis, D.
Siokou, A.
Kallitsis, I.
Galiotis, C.
[J]. CARBON, 2008, 46 (06) : 833 - 840
[8] Physico-chemical properties, kinetic parameters, and glucose inhibition of several beta-glucosidases for industrial applications
de Andrades, Diandra
Graebin, Natalia G.
Ayub, Marco A. Z.
Fernandez-Lafuente, Roberto
Rodrigues, Rafael C.
[J]. PROCESS BIOCHEMISTRY, 2019, 78 : 82 - 90
[9] Efficient lipase-catalyzed Knoevenagel condensation: utilization of biocatalytic promiscuity for synthesis of benzylidene-indolin-2-ones
Ding, Yan
Xiang, Xinran
Gu, Mengjie
Xu, Haoran
Huang, He
Hu, Yi
[J]. BIOPROCESS AND BIOSYSTEMS ENGINEERING, 2016, 39 (01) : 125 - 131
[10] Importance of the Support Properties for Immobilization or Purification of Enzymes
dos Santos, Jose Cleiton S.
Barbosa, Oveimar
Ortiz, Claudia
Berenguer-Murcia, Angel
Rodrigues, Rafael C.
Fernandez-Lafuente, Roberto
[J]. CHEMCATCHEM, 2015, 7 (16) : 2413 - 2432

← 1 2 3 4 5 →