An Intractable Case of Prototheca Keratitis and Chronic Endophthalmitis in Stevens-Johnson Syndrome With Boston Type 1 Keratoprosthesis

被引：0

作者：

Ng, Jacqueline ^{[1
]}

Minckler, Don ^{[1
,2
]}

Walsh, Thomas J. ^{[3
,4
,5
]}

Farid, Marjan ^{[1
]}

机构：

[1] Univ Calif Irvine, Gavin Herbert Eye Inst, 850 Hlth Sci Rd, Irvine, CA 92697 USA

[2] UCI Med Ctr, Dept Pathol, Orange, CA USA

[3] Cornell Univ, New York Presbyterian Hosp, Weill Cornell Med, Dept Med, New York, NY 10021 USA

[4] Cornell Univ, New York Presbyterian Hosp, Weill Cornell Med, Dept Pediat, New York, NY 10021 USA

[5] Cornell Univ, New York Presbyterian Hosp, Weill Cornell Med, Dept Microbiol & Immunol, New York, NY 10021 USA

来源：

CORNEA | 2016年 / 35卷 / 09期

关键词：

protothecosis; Boston keratoprosthesis; keratitis; endophthalmitis; Stevens-Johnson syndrome; WICKERHAMII ALGAEMIA; DOG;

D O I：

暂无

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Purpose: To report a case of recalcitrant Prototheca spp. keratitis and endophthalmitis in a patient with Stevens-Johnson syndrome (SJS) and Boston type 1 keratoprosthesis (B1 KPro). Methods: Case report. Results: A 67-year-old female with a history of SJS with chronic severe ocular surface disease in her monocular left eye underwent placement of a B1 KPro. Her course was subsequently complicated by persistent Prototheca spp. keratitis and endophthalmitis requiring ongoing treatment with triazole and polyene antifungal agents and multiple surgical revisions of her keratoprosthesis. Conclusions: Protothecosis is an algal infection that is rarely pathologic in humans, but when present can be difficult to manage. We present the second known case of persistent chronic Prototheca spp. keratitis and endophthalmitis in a patient with long-standing SJS and B1 KPro.

引用

页码：1257 / 1260

页数：4

共 13 条

[1]

[Anonymous], 1997, MYCOPATHOLOGIA, V137, P79

[2] Prototheca wickerhamii algaemia: an emerging infection in solid organ transplant recipients [J].

Bandaranayake, T. D. ;

Mondolfi, A. Paniz ;

Peaper, D. R. ;

Malinis, M. F. .

TRANSPLANT INFECTIOUS DISEASE, 2015, 17 (04) :599-604

[3] SUDDEN BLINDNESS ASSOCIATED WITH PROTOTHECOSIS IN A DOG [J].

BLOGG, JR ;

SYKES, JE .

AUSTRALIAN VETERINARY JOURNAL, 1995, 72 (04) :147-149

[4] Large-scale screening of the in vitro susceptibility of Prototheca zopfii towards polyene antibiotics [J].

Buzzini, Pietro ;

Turchetti, Benedetta ;

Branda, Eva ;

Goretti, Marta ;

Amici, Marco ;

Lagneau, Paul Emile ;

Scaccabarozzi, Licia ;

Bronzo, Valerio ;

Moroni, Paolo .

MEDICAL MYCOLOGY, 2008, 46 (05) :511-514

[5] METASTATIC PROTOTHECAL RETINITIS IN A DOG - ELECTRON-MICROSCOPIC OBSERVATIONS [J].

FONT, RL ;

HOOK, SR .

VETERINARY PATHOLOGY, 1984, 21 (01) :61-66

[6] Bilateral choroiditis from Prototheca wickerhamii algaemia [J].

Hariprasad, SM ;

Prasad, A ;

Smith, M ;

Shah, GK ;

Grand, MG ;

Shepherd, JB ;

Wickens, J ;

Apte, RS ;

Liao, RS ;

Van Gelder, R .

ARCHIVES OF OPHTHALMOLOGY, 2005, 123 (08) :1138-1141

[7] Human protothecosis [J].

Lass-Floerl, Cornelia ;

Mayr, Astrid .

CLINICAL MICROBIOLOGY REVIEWS, 2007, 20 (02) :230-+

[8] Protothecosis in hematopoietic stem cell transplantation: case report and review of previous cases [J].

Macesic, N. ;

Fleming, S. ;

Kidd, S. ;

Madigan, V. ;

Chean, R. ;

Ritchie, D. ;

Slavin, M. .

TRANSPLANT INFECTIOUS DISEASE, 2014, 16 (03) :490-495

[9] More tnan meets the eye: subretinal aspirate from an acutely blind dog [J].

Rizzi, Theresa E. ;

Cowell, Rick L. ;

Meinkoth, James H. ;

Gilmour, Margi A. .

VETERINARY CLINICAL PATHOLOGY, 2006, 35 (01) :111-113

[10] Prototheca wickerhamii Infection of a Corneal Graft [J].

Solky, Ana C. ;

Laver, Nora M. V. ;

Williams, Joseph ;

Fraire, Armando .

CORNEA, 2011, 30 (10) :1173-1175

← 1 2 →