Genetics of lipoprotein disorders

被引：67

作者：

Davignon, J

Genest, J

机构：

[1] Clin Res Inst Montreal, Hyperlipidemia & Atherosclerosis Res Grp, Montreal, PQ H2W 1R7, Canada

[2] Clin Res Inst Montreal, Cardiovasc Genet Lab, Montreal, PQ H2W 1R7, Canada

[3] Univ Montreal, Fac Med, Montreal, PQ H3C 3J7, Canada

[4] Montreal Univ Hosp, Med Ctr, Dept Med, Montreal, PQ, Canada

来源：

ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA | 1998年 / 27卷 / 03期

关键词：

D O I：

10.1016/S0889-8529(05)70024-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Many genes intervene in the homeostasis of plasma lipoprotein concentrations, which are also sensitive to environmental changes. Although many inherited disorders of lipoprotein metabolism are recognized, the genetic defect is known for only a few. For practical reasons, and until the genetic etiology is fully elucidated, it is best to classify these defects as a function of their major lipoprotein phenotype. Because of the life-threatening potential of some of these disorders, emphasis is placed on the atherogenic forms of dyslipoproteinemias.

引用

页码：521 / +

页数：32

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