P2O5 Promoted One-Pot Synthesis of 3-aminoimidazo[1,2-a]pyridines under Solvent-Free Conditions

被引：2
作者：
Soleimani, Ebrahim [1 ]
Taran, Mojtaba [2 ]
Zainali, Mohsen [1 ]
Lotfi, Shahram [3 ]
机构：
[1] Razi Univ, Dept Chem, Kermanshah 67149, Iran
[2] Razi Univ, Dept Biol, Kermanshah 6714967346, Iran
[3] Payame Noor Univ, Dept Chem, Tehran, Iran
来源：
LETTERS IN ORGANIC CHEMISTRY | 2012年 / 9卷 / 03期
基金：
美国国家科学基金会;
关键词：
Imidazo[1,2-a]pyridine; P2O5; 2-Aminopyridine; Isocyanide; 3-COMPONENT CONDENSATION; FUSED; 3-AMINOIMIDAZOLES; ANNULATED PYRIDINES; PYRAZINES; PYRIMIDINES;
D O I：
10.2174/157017812800167411
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A facile, efficient and environment-friendly protocol for the synthesis of 3-aminoimidazo[1,2-a]pyridines has been developed by one-pot condensation of 2-aminopyridine, aromatic aldehyde and alkyl or aryl isocyanide in the presence of P2O5 as catalyst under solvent-free conditions at room temperature. The present approach offers the advantages of clean reaction, simple methodology, short reaction time, high yield, easy purification, and economic availability of the catalyst.
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收藏
页码：198 / 201
页数：4
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