The non-evaginated secondary prosencephalon of vertebrates

被引:42
作者
Moreno, Nerea [1 ]
Gonzalez, Agustin [1 ]
机构
[1] Univ Complutense Madrid, Fac Biol, Dept Biol Celular, E-28040 Madrid, Spain
关键词
preoptic area; hypothalamus; development; homology; tetrapods; LIM-HOMEODOMAIN GENES; NEURAL PLATE; REGULATORY GENES; XENOPUS-LAEVIS; SONIC-HEDGEHOG; BASAL GANGLIA; MAMMALIAN TELENCEPHALON; DEVELOPING FOREBRAIN; EXPRESSION PATTERNS; REGIONAL EXPRESSION;
D O I
10.3389/fnana.2011.00012
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100101 ;
摘要
The secondary prosencephalon (telencephalon plus hypothalamus) is probably the most complex area of the brain, with complicated patterning specifications. As yet, no prosomeric subdivisions have been reported and only distinct histogenetic territories have been recognized. In the present comparative study we analyzed cross-correlated expression maps in the non-evaginated territories of the secondary prosencephalon in different vertebrates throughout development, to assess the existence of comparable divisions and subdivisions in the different groups. Each division is characterized by expression of a unique combination of developmental regulatory genes, and each appears to represent a self-regulated and topologically constant histogenetic brain compartment that gives rise to a specific cell group. The non-evaginated area of the telencephalon corresponds to the preoptic region, whereas the hypothalamus, topologically rostral to the diencephalic prethalamus, includes basal (mammillary and tuberal) and alar (paraventricular and suprachiasmatic) parts. This complex area is specified by a cascade of transcription factors, among which the Dlx family members and Nkx2.1 are essential for the correct development. The only exception is found in the subdivision named termed the supraoptoparaventricular area, in which the transcription factor Orthopedia is essential in restricting the fate of multiple categories of neuroendocrine neurons, in the absence of the Dlx/Nkx2.1 combination. Our analysis, based on own data and published results by other researchers, suggests that common features are shared at least by all tetrapods and, therefore, they most likely were present in the stem tetrapods. The available data for agnathans (lampreys) and other fish groups indicate that not all subdivisions of the secondary prosencephalon were present at the origin of vertebrates, raising important questions about their evolution.
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页数:9
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共 102 条
[1]   Subdivisions and Derivatives of the Chicken Subpallium Based on Expression of LIM and Other Regulatory Genes and Markers of Neuron Subpopulations During Development [J].
Abellan, Antonio ;
Medina, Loreta .
JOURNAL OF COMPARATIVE NEUROLOGY, 2009, 515 (04) :465-501
[2]   Progressive impairment of developing neuroendocrine cell lineages in the hypothalamus of mice lacking the Orthopedia gene [J].
Acampora, D ;
Postiglione, MP ;
Avantaggiato, V ;
Di Bonito, M ;
Vaccarino, FM ;
Michaud, J ;
Simeone, A .
GENES & DEVELOPMENT, 1999, 13 (21) :2787-2800
[3]  
[Anonymous], 2005, Comparative Vertebrate Neuroanatomy: Evolution and Adaptation
[4]   A LIM-homeodomain code for development and evolution of forebrain connectivity [J].
Bachy, I ;
Failli, V ;
Rétaux, S .
NEUROREPORT, 2002, 13 (02) :A23-A27
[5]   The LIM-homeodomain gene family in the developing Xenopus brain:: Conservation and divergences with the mouse related to the evolution of the forebrain [J].
Bachy, I ;
Vernier, P ;
Rétaux, S .
JOURNAL OF NEUROSCIENCE, 2001, 21 (19) :7620-7629
[6]   Chicken lateral septal organ and other circumventricular organs form in a striatal subdomain abutting the molecular striatopallidal border [J].
Bardet, S. M. ;
Cobos, I. ;
Puelles, E. ;
Martinez-De-La-Torre, M. ;
Puelles, L. .
JOURNAL OF COMPARATIVE NEUROLOGY, 2006, 499 (05) :745-767
[7]   Conserved pattern of OTP-positive cells in the paraventricular nucleus and other hypothalamic sites of tetrapods [J].
Bardet, Sylvia M. ;
Martinez-de-la-Torre, Margaret ;
Northcutt, R. Glenn ;
Rubenstein, John L. R. ;
Puelles, Luis .
BRAIN RESEARCH BULLETIN, 2008, 75 (2-4) :231-235
[8]   Ontogenetic expression of Sonic hedgehog in the chicken subpallium [J].
Bardet, Sylvia M. ;
Ferran, Jose L. E. ;
Sanchez-Arrones, Luisa ;
Puelles, Luis .
FRONTIERS IN NEUROANATOMY, 2010, 4
[9]   Specification of hypothalamic neurons by dual regulation of the homeodomain protein Orthopedia [J].
Blechman, Janna ;
Borodovsky, Nataliya ;
Eisenberg, Mark ;
Nabel-Rosen, Helit ;
Grimm, Jan ;
Levkowitz, Gil .
DEVELOPMENT, 2007, 134 (24) :4417-4426
[10]   Complete mitochondrial genome sequences of the South American and the Australian lungfish: Testing of the phylogenetic performance of mitochondrial data sets for phylogenetic problems in tetrapod relationships [J].
Brinkmann, H ;
Denk, A ;
Zitzler, J ;
Joss, JJ ;
Meyer, A .
JOURNAL OF MOLECULAR EVOLUTION, 2004, 59 (06) :834-848