Socioeconomic status and prevalence of congenital heart defects: Does universal access to health care system eliminate the gap?

被引:46
作者
Agha, Mohammad M. [1 ,2 ,3 ,8 ]
Glazier, Richard H. [1 ,2 ,4 ,8 ]
Moineddin, Rahim [1 ,2 ,4 ]
Moore, Aideen M. [5 ,6 ,7 ]
Guttmann, Astrid [1 ,5 ,6 ,7 ]
机构
[1] Inst Clin Evaluat Sci, Toronto, ON M4N 3M5, Canada
[2] Univ Toronto, St Michaels Hosp, Ctr Res Inner City Hlth, Toronto, ON M5B 1W8, Canada
[3] Univ Toronto, Paediat Oncol Grp Ontario, Toronto, ON, Canada
[4] Univ Toronto, Dept Family & Community Med, Toronto, ON M5S 1A1, Canada
[5] Univ Toronto, Hosp Sick Children, Div Paediat Med, Toronto, ON M5G 1X8, Canada
[6] Univ Toronto, Fac Med, Dept Paediat, Toronto, ON, Canada
[7] Univ Toronto, Fac Med, Dept Hlth Policy, Dept Hlth Policy Management & Evaluat, Toronto, ON, Canada
[8] Univ Toronto, Dalla Lana Sch Publ Hlth, Toronto, ON, Canada
关键词
congenital anomalies; Congenital heart defects; socioeconomic status; Time Trend; Access to health care system; FOLIC-ACID FORTIFICATION; NEURAL-TUBE DEFECTS; BIRTH-DEFECTS; CARDIOVASCULAR MALFORMATIONS; RISK; DISEASE; ASSOCIATION; TRENDS; MULTIVITAMIN; DIAGNOSIS;
D O I
10.1002/bdra.22857
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
BACKGROUND: A twofold increase in the prevalence of congenital heart defects (CHDs) has been reported since the early 1970s with higher rates among children from low socioeconomic status (SES). This increase and the observed SES gap are postulated to be reflective of higher ascertainment, especially increased use of ultrasound and echography. The purpose of this study was to examine if trends over time in the prevalence of CHD were the same for high and low SES groups. METHODS: Using the child's health number as a unique identifier and through record linkage, children born in Ontario between 1994 and 2007 were followed for the diagnosis of CHD. Using postal codes and census information, SES quintiles were assigned to each child. We used adjusted rates and used multivariate models to compare trends in the prevalence rate among children born in different SES groups. RESULTS: Children born in low SES areas (23% of all births) had significantly higher rates of CHDs (rate ratio = 1.20; 95% confidence interval [CI] = 1.151.24). While prevalence of nonsevere CHDs declined in all SES groups since 2000, severe CHDs, especially atrial septal defects were on the rise during the study period. DISCUSSION: It is assumed that increased ascertainment is responsible for observed increase in the prevalence of CHD, especially minor defects. While the trend and pattern over time changed for severe and nonsevere CHDs, the SES gap remained consistent during the study period. Our results indicate that even free and universal access to a health care system does not eliminate the SES gap observed in the prevalence of CHD. Birth Defects Research (Part A) 2011. (C) 2011 Wiley Periodicals, Inc.
引用
收藏
页码:1011 / 1018
页数:8
相关论文
共 34 条
[1]  
Botto L.D., 2003, Progress in Pediatric Cardiology, V18, P111, DOI [10.1016/S1058-9813(03)00084-5, DOI 10.1016/S1058-9813(03)00084-5]
[2]   Racial and temporal variations in the prevalence of heart defects [J].
Botto, LD ;
Correa, A ;
Erickson, JD .
PEDIATRICS, 2001, 107 (03) :E32
[3]  
Botto LD, 1996, PEDIATRICS, V98, P911
[4]   Do multivitamin or folic acid supplements reduce the risk for congenital heart defects? Evidence and gaps [J].
Botto, LD ;
Mulinare, J ;
Erickson, JD .
AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 2003, 121A (02) :95-101
[5]   Socio-economic status and risk of conotruncal heart defects and orofacial clefts [J].
Carmichael, SL ;
Nelson, V ;
Shaw, GM ;
Wasserman, CR ;
Croen, LA .
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY, 2003, 17 (03) :264-271
[6]   Socioeconomic Measures, Orofacial Clefts, and Conotruncal Heart Defects in California [J].
Carmichael, Suzan L. ;
Ma, Chen ;
Shaw, Gary M. .
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 2009, 85 (10) :850-857
[7]   The metropolitan Atlanta congenital defects program:: 35 years of birth defects surveillance at the centers for disease control and prevention [J].
Correa-Villaseñor, A ;
Cragan, J ;
Kucik, J ;
O'Leary, L ;
Siffel, C ;
Williams, L .
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 2003, 67 (09) :617-624
[8]   Descriptive epidemiology of congenital heart disease in Northern England [J].
Dadvand, Payam ;
Rankin, Judith ;
Shirley, Mark D. F. ;
Rushton, Stephen ;
Pless-Mulloli, Tanja .
PAEDIATRIC AND PERINATAL EPIDEMIOLOGY, 2009, 23 (01) :58-65
[9]   Spina bifida before and after folic acid fortification in Canada [J].
De Wals, Philippe ;
Tairou, Fassiatou ;
Van Allen, Margot I. ;
Lowry, R. Brian ;
Evans, Jane A. ;
Van den Hof, Michiel C. ;
Crowley, Marian ;
Uh, Soo-Hong ;
Zimmer, Pamela ;
Sibbald, Barbara ;
Fernandez, Bridget ;
Lee, Nora S. ;
Niyonsenga, Theophile .
BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY, 2008, 82 (09) :622-626
[10]   Reduction in neural-tube defects after folic acid fortification in Canada [J].
De Wals, Philippe ;
Tairou, Fassiatou ;
Van Allen, Margot I. ;
Uh, Soo-Hong ;
Lowry, R. Brian ;
Sibbald, Barbara ;
Evans, Jane A. ;
Van den Hof, Michiel C. ;
Zimmer, Pamela ;
Crowley, Marian ;
Fernandez, Bridget ;
Lee, Nora S. ;
Niyonsenga, Theophile .
NEW ENGLAND JOURNAL OF MEDICINE, 2007, 357 (02) :135-142