Delayed Relapse of Paracoccidioidomycosis in the Central Nervous System: A Case Report

被引：4
|
作者：
Rahman, Rifat [1 ]
Davies, Leela [2 ,3 ,4 ]
Mohareb, Amir M. [2 ,3 ,4 ]
Pecanha-Pietrobom, Paula M. [5 ]
Patel, Nirav J. [6 ]
Solomon, Isaac H. [7 ]
Meredith, David M. [7 ]
Tsai, Harrison K. [7 ]
Guenette, Jeffrey P. [8 ]
Bhattacharyya, Shamik [9 ]
Urday, Sebastian [9 ]
Velasquez, Gustavo E. [2 ,10 ,11 ]
机构：
[1] Harvard Med Sch, Boston, MA 02115 USA
[2] Brigham & Womens Hosp, Div Infect Dis, 75 Francis St, Boston, MA 02115 USA
[3] Massachusetts Gen Hosp, Div Infect Dis, Boston, MA 02114 USA
[4] Harvard Med Sch, Dept Med, Boston, MA 02115 USA
[5] Univ Fed Sao Paulo, Div Infect Dis, Sao Paulo, Brazil
[6] Brigham & Womens Hosp, Dept Neurosurg, 75 Francis St, Boston, MA 02115 USA
[7] Brigham & Womens Hosp, Dept Pathol, 75 Francis St, Boston, MA 02115 USA
[8] Brigham & Womens Hosp, Div Neurosurg, 75 Francis St, Boston, MA 02115 USA
[9] Brigham & Womens Hosp, Dept Neurol, 75 Francis St, Boston, MA 02115 USA
[10] Harvard Med Sch, Dept Global Hlth & Social Med, 641 Huntington Ave, Boston, MA 02115 USA
[11] Brigham & Womens Hosp, Div Global Hlth Equ, 75 Francis St, Boston, MA 02115 USA
来源：
OPEN FORUM INFECTIOUS DISEASES | 2020年 / 7卷 / 04期
基金：
美国国家卫生研究院;
关键词：
central nervous system; endemic mycosis; neuroparacoccidioidomycosis; Paracoccidioides brasiliensis; paracoccidioidomycosis; HUMAN-IMMUNODEFICIENCY-VIRUS; ITRACONAZOLE;
D O I：
10.1093/ofid/ofaa077
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Paracoccidioidomycosis is a dimorphic fungal infection endemic in Latin America. We report a patient with a history of pulmonary paracoccidioidomycosis who presented with relapsed disease in the central nervous system 4 years after initial treatment. We review current treatment strategies for paracoccidioidomycosis and neuroparacoccidioidomycosis.
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页数：3
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