Skull Base Chordomas

被引：45

作者：

Koutourousiou, Maria ^{[2
]}

Snyderman, Carl H. ^{[1
,2
]}

Fernandez-Miranda, Juan ^{[2
]}

Gardner, Paul A. ^{[2
]}

机构：

[1] Univ Pittsburgh, Sch Med, Dept Otolaryngol, Pittsburgh, PA 15213 USA

[2] Univ Pittsburgh, Sch Med, Dept Neurol Surg, Pittsburgh, PA 15213 USA

来源：

OTOLARYNGOLOGIC CLINICS OF NORTH AMERICA | 2011年 / 44卷 / 05期

关键词：

Chordoma; Clivus; Endonasal skull base surgery; Endoscopic skull base surgery; EXPANDED ENDONASAL APPROACH; TECHNICAL CASE-REPORT; UPPER CERVICAL-SPINE; TERM-FOLLOW-UP; CRANIAL BASE; RADIATION-THERAPY; CLIVAL CHORDOMAS; NASOSEPTAL FLAP; CRANIOCERVICAL JUNCTION; CHONDROID CHORDOMA;

D O I：

10.1016/j.otc.2011.06.002

中图分类号：

R76 [耳鼻咽喉科学];

学科分类号：

100213 ;

摘要：

Skull base chordomas are rare midline malignancies of clival origin that represent one of the most challenging skull base tumors to treat, given their location, invasiveness, potential extension around vital neurovascular structures, and high recurrence rate. Total tumor resection is the mainstay of treatment. The combination of surgery and postoperative irradiation appears to provide the best outcome.

引用

页码：1155 / +

页数：18

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