Targeted next-generation sequencing of familial platelet disorder with predisposition to acute myeloid leukaemia

被引：16
作者：
Haslam, Karl [1 ]
Langabeer, Stephen E. [1 ]
Hayat, Amjad [2 ]
Conneally, Eibhlin [3 ]
Vandenberghe, Elisabeth [1 ,3 ]
机构：
[1] St James Hosp, Canc Mol Diagnost, Dublin, Ireland
[2] Galway Univ Hosp, Dept Haematol, Galway, Ireland
[3] St James Hosp, Dept Haematol, Dublin, Ireland
来源：
BRITISH JOURNAL OF HAEMATOLOGY | 2016年 / 175卷 / 01期
关键词：
FPD-AML; RUNX1; next-generation sequencing; ACUTE MYELOGENOUS LEUKEMIA; PROPENSITY; MUTATIONS; SECONDARY; FPD/AML; RUNX1;
D O I：
10.1111/bjh.13838
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：161 / 163
页数：3
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  • [1] Proposal for the clinical detection and management of patients and their family members with familial myelodysplastic syndrome/acute leukemia predisposition syndromes
    Churpek, Jane E.
    Lorenz, Rachelle
    Nedumgottil, Siya
    Onel, Kenan
    Olopade, Olufunmilayo I.
    Sorrell, April
    Owen, Carolyn J.
    Bertuch, Alison A.
    Godley, Lucy A.
    [J]. LEUKEMIA & LYMPHOMA, 2013, 54 (01) : 28 - 35
  • [2] Perspectives for therapeutic targeting of gene mutations in acute myeloid leukaemia with normal cytogenetics
    Falini, Brunangelo
    Sportoletti, Paolo
    Brunetti, Lorenzo
    Martelli, Maria Paola
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2015, 170 (03) : 305 - 322
  • [3] Familial platelet disorder with propensity to acute myelogenous leukemia: Genetic heterogeneity and progression to leukemia via acquisition of clonal chromosome anomalies
    Minelli, A
    Maserati, E
    Rossi, G
    Bernardo, ME
    De Stefano, P
    Cecchini, MP
    Valli, R
    Albano, V
    Pierani, P
    Leszl, A
    Sainati, L
    Lo Curto, F
    Danesino, C
    Locatelli, F
    Pasquali, F
    [J]. GENES CHROMOSOMES & CANCER, 2004, 40 (03) : 165 - 171
  • [4] Recognizing familial myeloid leukemia in adults
    Nickels, Eric M.
    Soodalter, Jesse
    Churpek, Jane E.
    Godley, Lucy A.
    [J]. THERAPEUTIC ADVANCES IN HEMATOLOGY, 2013, 4 (04) : 254 - 269
  • [5] Whole-exome sequencing confirmation of a novel heterozygous mutation in RUNX1 in a pregnant woman with platelet disorder
    Obata, Miyuki
    Tsutsumi, Seiji
    Makino, Satoshi
    Takahashi, Kanako
    Watanabe, Norikazu
    Yoshida, Takayuki
    Tamiya, Gen
    Kurachi, Hirohisa
    [J]. PLATELETS, 2015, 26 (04) : 364 - 369
  • [6] High frequency of RUNX1 biallelic alteration in acute myeloid leukemia secondary to familial platelet disorder
    Preudhomme, Claude
    Renneville, Aline
    Bourdon, Violaine
    Philippe, Nathalie
    Roche-Lestienne, Catherine
    Boissel, Nicolas
    Dhedin, Nathalie
    Andre, Jean-Marie
    Cornillet-Lefebvre, Pascale
    Baruchel, Andre
    Mozziconacci, Marie-Joelle
    Sobol, Hagay
    [J]. BLOOD, 2009, 113 (22) : 5583 - 5587
  • [7] CBL mutation in chronic myelomonocytic leukemia secondary to familial platelet disorder with propensity to develop acute myeloid leukemia (FPD/AML)
    Shiba, Norio
    Hasegawa, Daisuke
    Park, Myoung-ja
    Murata, Chisato
    Sato-Otsubo, Aiko
    Ogawa, Chitose
    Manabe, Atsushi
    Arakawa, Hirokazu
    Ogawa, Seishi
    Hayashi, Yasuhide
    [J]. BLOOD, 2012, 119 (11) : 2612 - 2614
  • [8] Haploinsufficiency of CBFA2 causes familial thrombocytopenia with propensity to develop acute myelogenous leukaemia
    Song, WJ
    Sullivan, MG
    Legare, RD
    Hutchings, S
    Tan, XL
    Kufrin, D
    Ratajczak, J
    Resende, IC
    Haworth, C
    Hock, R
    Loh, M
    Felix, C
    Roy, DC
    Busque, L
    Kurnit, D
    Willman, C
    Gewirtz, AM
    Speck, NA
    Bushweller, JH
    Li, FP
    Gardiner, K
    Poncz, M
    Maris, JM
    Gilliland, DG
    [J]. NATURE GENETICS, 1999, 23 (02) : 166 - 175
  • [9] Disease evolution and outcomes in familial AML with germline CEBPA mutations
    Tawana, Kiran
    Wang, Jun
    Renneville, Aline
    Bodor, Csaba
    Hills, Robert
    Loveday, Chey
    Savic, Aleksandar
    Van Delft, Frederik W.
    Treleaven, Jennifer
    Georgiades, Panayiotis
    Uglow, Elizabeth
    Asou, Norio
    Uike, Naokuni
    Debeljak, Marusa
    Jazbec, Janez
    Ancliff, Philip
    Gale, Rosemary
    Thomas, Xavier
    Mialou, Valerie
    Doehner, Konstanze
    Bullinger, Lars
    Mueller, Beatrice
    Pabst, Thomas
    Stelljes, Matthias
    Schlegelberger, Brigitte
    Wozniak, Eva
    Iqbal, Sameena
    Okosun, Jessica
    Araf, Shamzah
    Frank, Anne-Katrine
    Lauridsen, Felicia B.
    Porse, Bo
    Nerlov, Claus
    Owen, Carolyn
    Dokal, Inderjeet
    Gribben, John
    Smith, Matthew
    Preudhomme, Claude
    Chelala, Claude
    Cavenagh, Jamie
    Fitzgibbon, Jude
    [J]. BLOOD, 2015, 126 (10) : 1214 - 1223
  • [10] Recurrent CDC25C mutations drive malignant transformation in FPD/AML
    Yoshimi, Akihide
    Toya, Takashi
    Kawazu, Masahito
    Ueno, Toshihide
    Tsukamoto, Ayato
    Iizuka, Hiromitsu
    Nakagawa, Masahiro
    Nannya, Yasuhito
    Arai, Shunya
    Harada, Hironori
    Usuki, Kensuke
    Hayashi, Yasuhide
    Ito, Etsuro
    Kirito, Keita
    Nakajima, Hideaki
    Ichikawa, Motoshi
    Mano, Hiroyuki
    Kurokawa, Mineo
    [J]. NATURE COMMUNICATIONS, 2014, 5
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