Immuno-Oncology beyond TILs: Unleashing TILCs

被引：11
作者：
Demaria, Olivier [1 ]
Vivier, Eric [1 ,2 ,3 ]
机构：
[1] Innate Pharma, Innate Pharma Res Labs, Marseille, France
[2] Aix Marseille Univ, CNRS, INSERM, CIML, Marseille, France
[3] Hop La Timone, AP HM, Marseille Immunopole, Serv Immunol, Marseille, France
来源：
CANCER CELL | 2020年 / 37卷 / 04期
基金：
欧洲研究理事会;
关键词：
CELLS;
D O I：
10.1016/j.ccell.2020.03.021
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Innate lymphoid cells (ILCs) are detected in multiple tumor types, but their contribution to tumor immunity remains unclear. Moral et al. show that a subset of tumor ILCs (TILCs) may participate in an organ-specific immune response and can be unleashed by PD-1 blockers to sustain tumor-specific T cell responses.
引用
收藏
页码：428 / 430
页数：3
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