Enhancement of paclitaxel production by abscisic acid in cell suspension cultures of Taxus chinensis

被引：32
|
作者：
Luo, J [1 ]
Liu, L [1 ]
Wu, CD [1 ]
机构：
[1] Huazhong Univ Sci & Technol, Sch Life Sci & Technol, Wuhan 430074, Peoples R China
来源：
BIOTECHNOLOGY LETTERS | 2001年 / 23卷 / 16期
关键词：
abscisic acid; Paclitaxel; plant cell culture; Taxus chinensis;
D O I：
10.1023/A:1010597802741
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Addition of 5 mg abscisic acid l(-1) after 12 days' growth of Taxus chinensis suspension culture gave the greatest paclitaxel accumulation at 11 mg l(-1), which was almost 5 times that of the control culture. The highest paclitaxel production, 18 mg l(-1), was obtained using 5 mg abscisic acid l(-1) and 20 mg methyl jasmonate l(-1).
引用
收藏
页码：1345 / 1348
页数：4
相关论文
共 50 条
  • [31] Cell death unlikely contributes to Taxol production in fungal elicitor-induced cell suspension cultures of Taxus chinensis
    Lan, WZ
    Yu, LJ
    Li, MY
    Qin, WM
    BIOTECHNOLOGY LETTERS, 2003, 25 (01) : 47 - 49
  • [32] Significant improvement of taxane production in suspension cultures of Taxus chinensis by sucrose feeding strategy
    Wang, HQ
    Yu, JT
    Zhong, JJ
    PROCESS BIOCHEMISTRY, 2000, 35 (05) : 479 - 483
  • [33] Ultrasound-assisted fractional precipitation of paclitaxel from Taxus chinensis cell cultures
    Seo, Hye-Won
    Kim, Jin-Hyun
    PROCESS BIOCHEMISTRY, 2019, 87 : 238 - 243
  • [34] Quantitative Influence of Endogenous Salicylic Acid Level on Taxuyunnanine C Biosynthesis in Suspension Cultures of Taxus chinensis
    Zhou, Xin
    Zhong, Jian-Jiang
    BIOTECHNOLOGY AND BIOENGINEERING, 2011, 108 (01) : 216 - 221
  • [35] Recovery of extracellular paclitaxel from suspension culture of Taxus chinensis by adding inorganic salts
    Son, JS
    Choi, HK
    Hong, SS
    BIOTECHNOLOGY LETTERS, 2001, 23 (09) : 723 - 725
  • [36] Enhancement of taxol production and release in Taxus chinensis cell cultures by ultrasound, methyl jasmonate and in situ solvent extraction
    J. Wu
    L. Lin
    Applied Microbiology and Biotechnology, 2003, 62 : 151 - 155
  • [37] Scale-up study on suspension cultures of Taxus chinensis cells for production of taxane diterpene
    Pan, ZW
    Wang, HQ
    Zhong, JJ
    ENZYME AND MICROBIAL TECHNOLOGY, 2000, 27 (09) : 714 - 723
  • [38] Taxoids from cell cultures of Taxus chinensis
    Menhard, B
    Eisenreich, W
    Hylands, PJ
    Bacher, A
    Zenk, MH
    PHYTOCHEMISTRY, 1998, 49 (01) : 113 - 125
  • [39] Elucidation of the Mechanism and Kinetics of Ultrasonic Extraction of Paclitaxel from Plant Cell Cultures of Taxus chinensis
    Hak-Gyun Kim
    Jin-Hyun Kim
    Biotechnology and Bioprocess Engineering, 2022, 27 : 668 - 677
  • [40] Optimization of Adsorbent Treatment Process for the Purification of Paclitaxel from Plant Cell Cultures of Taxus chinensis
    Lee, Chung-Gi
    Kim, Jin-Hyun
    KOREAN CHEMICAL ENGINEERING RESEARCH, 2014, 52 (04): : 497 - 502
12345