Enhancement of paclitaxel production by abscisic acid in cell suspension cultures of Taxus chinensis

被引：32
|
作者：
Luo, J [1 ]
Liu, L [1 ]
Wu, CD [1 ]
机构：
[1] Huazhong Univ Sci & Technol, Sch Life Sci & Technol, Wuhan 430074, Peoples R China
来源：
BIOTECHNOLOGY LETTERS | 2001年 / 23卷 / 16期
关键词：
abscisic acid; Paclitaxel; plant cell culture; Taxus chinensis;
D O I：
10.1023/A:1010597802741
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
Addition of 5 mg abscisic acid l(-1) after 12 days' growth of Taxus chinensis suspension culture gave the greatest paclitaxel accumulation at 11 mg l(-1), which was almost 5 times that of the control culture. The highest paclitaxel production, 18 mg l(-1), was obtained using 5 mg abscisic acid l(-1) and 20 mg methyl jasmonate l(-1).
引用
收藏
页码：1345 / 1348
页数：4
相关论文
共 50 条
  • [21] Optimization of elicitors and precursors for paclitaxel production in cell suspension culture of Taxus chinensis in the presence of nutrient feeding
    Luo, J
    He, GY
    PROCESS BIOCHEMISTRY, 2004, 39 (09) : 1073 - 1079
  • [22] Repeated elicitation enhances taxane production in suspension cultures of Taxus chinensis in bioreactors
    Zhen-Yu Wang
    Jian-Jiang Zhong
    Biotechnology Letters, 2002, 24 : 445 - 448
  • [23] Significant improvement of taxane production in suspension cultures of Taxus chinensis by combining elicitation with sucrose feed
    Dong, HD
    Zhong, JJ
    BIOCHEMICAL ENGINEERING JOURNAL, 2001, 8 (02) : 145 - 150
  • [24] Novel synthetic jasmonates as highly efficient elicitors for taxoid production by suspension cultures of Taxus chinensis
    Qian, ZG
    Zhao, ZJ
    Tian, WH
    Xu, YF
    Zhong, JJ
    Qian, XH
    BIOTECHNOLOGY AND BIOENGINEERING, 2004, 86 (05) : 595 - 599
  • [25] Efficient purification and morphology characterization of paclitaxel from cell cultures of Taxus chinensis
    Pyo, SH
    Kim, MS
    Cho, JS
    Song, BK
    Han, BH
    Choi, HJ
    JOURNAL OF CHEMICAL TECHNOLOGY AND BIOTECHNOLOGY, 2004, 79 (10) : 1162 - 1168
  • [26] Intermittent maltose feeding enhances paclitaxel production in suspension culture of Taxus chinensis cells
    Hyung-Kyoon Choi
    Sang-Ic Kim
    Joo-Sun Son
    Seung-Suh Hong
    Hyun-Soo Lee
    In-Sik Chung
    Hyong-Joo Lee
    Biotechnology Letters, 2000, 22 : 1793 - 1796
  • [27] Fractional precipitation for paclitaxel pre-purification from plant cell cultures of Taxus chinensis
    Jin-Hyun Kim
    In-Seon Kang
    Hyung-Kyoon Choi
    Seung-Suh Hong
    Hyun-Soo Lee
    Biotechnology Letters, 2000, 22 : 1753 - 1756
  • [28] Enhanced production of paclitaxel by semi-continuous batch process (SCBP) in suspension culture of Taxus chinensis
    Choi, HK
    Yun, JH
    Kim, SI
    Son, JS
    Kim, HR
    Kim, JH
    Choi, HJ
    Hong, SS
    ENZYME AND MICROBIAL TECHNOLOGY, 2001, 29 (10) : 583 - 586
  • [29] Fractional precipitation for paclitaxel pre-purification from plant cell cultures of Taxus chinensis
    Kim, JH
    Kang, IS
    Choi, HK
    Hong, SS
    Lee, HS
    BIOTECHNOLOGY LETTERS, 2000, 22 (22) : 1753 - 1756
  • [30] Effect of mixing time on taxoid production using suspension cultures of Taxus chinensis in a centrifugal impeller bioreactor
    Zhong, JJ
    Pan, ZW
    Wang, ZY
    Wu, JY
    Chen, F
    Takagi, M
    Yoshida, T
    JOURNAL OF BIOSCIENCE AND BIOENGINEERING, 2002, 94 (03) : 244 - 250
12345