Effects of a Plum (Prunus mume Siebold and Zucc.) Ethanol Extract on the Immune System in Vivo and in Vitro

被引：16

作者：

Tsuji, Ryohei ^{[1
]}

Koizumi, Hideki ^{[1
]}

Fujiwara, Daisuke ^{[1
]}

机构：

[1] Kirin Holdings Co Ltd, Cent Labs Frontier Technol, Kanazawa Ku, Kanagawa 2360004, Japan

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2011年 / 75卷 / 10期

关键词：

plum ethanol extract; innate immunity; immune enhancement; interleukin-12; ripeness; FRUIT-JUICE CONCENTRATE; JAPANESE APRICOT; INHIBITION; INFECTION;

D O I：

10.1271/bbb.100886

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The effect of a plum ethanol extract (PEE) on immunity was analyzed. An oral administration of PEE increased the interleukin (IL)-12p40 concentration in the serum and T-cell ratio in the spleen. In vitro studies revealed that PEE stimulated IL-12p70 production in peritoneal macrophages and natural killer activity. These findings suggest that PEE enhanced the immune function by stimulating innate immune cells.

引用

页码：2011 / 2013

页数：3

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