Ruthenium-Catalyzed Hydroarylations of Oxa- and Azabicyclic Alkenes

被引：65

作者：

Cheng, Hanchao ^{[1
]}

Dong, Wanrong ^{[1
]}

Dannenberg, Carl Albrecht ^{[1
]}

Dong, Shunxi ^{[1
]}

Guo, Qianqian ^{[2
]}

Bolm, Carsten ^{[1
]}

机构：

[1] Rhein Westfal TH Aachen, Inst Organ Chem, D-52056 Aachen, Germany

[2] Rhein Westfal TH Aachen, Inst Inorgan Chem, D-52056 Aachen, Germany

来源：

ACS CATALYSIS | 2015年 / 5卷 / 05期

关键词：

ruthenium; alkylation; oxa- and azabicyclic alkenes; oxygen; C-H bond activation; H BOND FUNCTIONALIZATION; RING-OPENING REACTIONS; C-C; ASYMMETRIC-SYNTHESIS; OXABICYCLIC ALKENES; METAL; ARENES; FLUORINATION; ACTIVATION; C(SP(2))-H;

D O I：

10.1021/acscatal.5b00258

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

A ruthenium-catalyzed arylation reaction of oxa- and azabicyclic alkenes with (hetero)arenes by C-H bond activation has been discovered. The reaction does not require additives and utilizes dioxygen in realizing the catalytic cycle leading to monosubstituted 7-oxa and 7-azabenzonor-bornane derivatives.

引用

页码：2770 / 2773

页数：4

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