Visible-light-mediated radical oxydifluoromethylation of olefinic amides for the synthesis of CF2H-containing heterocycles

被引：141

作者：

Fu, Weijun ^{[1
,2
]}

Han, Xin ^{[3
]}

Zhu, Mei ^{[1
,2
]}

Xu, Chen ^{[1
,2
]}

Wang, Zhiqiang ^{[1
,2
]}

Ji, Baoming ^{[1
,2
]}

Hao, Xin-Qi ^{[3
]}

Song, Mao-Ping ^{[3
]}

机构：

[1] Luoyang Normal Univ, Coll Chem & Chem Engn, Luoyang 471022, Henan, Peoples R China

[2] Luoyang Normal Univ, Henan Key Lab Funct Oriented Porous Mat, Luoyang 471022, Henan, Peoples R China

[3] Zhengzhou Univ, Coll Chem & Mol Engn, Zhengzhou 450052, Henan, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2016年 / 52卷 / 91期

基金：

中国国家自然科学基金;

关键词：

DIRECT DIFLUOROMETHYLATION; CATALYZED TRIFLUOROMETHYLATION; PHOTOREDOX CATALYSIS; ARYL; ALKENES; INHIBITORS; FLUOROFORM; FLUORINE; ARYLDIFLUOROACETYLATION; FUNCTIONALIZATION;

D O I：

10.1039/c6cc07771d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The visible-light-mediated oxydifluoromethylation of olefinic amides with difluoromethyl sulfones has been explored. This method allows for an efficient and practical synthesis of a variety of CF2H-containing benzoxazines and oxazolines bearing various functional groups under mild conditions.

引用

页码：13413 / 13416

页数：4

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